⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1345387 | 0.97 | — | — | |
| SCHEMBL1129630 | 0.84 | MAPT (0.55) | — | |
| SCHEMBL73482 | 0.77 | — | — | |
| SCHEMBL6169033 | 0.76 | RAB9A (0.46) | — | |
| SCHEMBL127369 | 0.75 | IDO1 (0.69) | — | |
| Pyridine SCHEMBL27170372 | 0.75 | IDO1 (0.50) | — | |
| Hydrochloric Acid SCHEMBL258153 | 0.75 | LOXL2 (0.54) | — | |
| SCHEMBL151822 | 0.73 | LOXL2 (0.68) | — | |
| SCHEMBL721736 | 0.73 | CYP17A1 (0.61) | — | |
| SCHEMBL842668 | 0.73 | HRH1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 419 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667611-B2 | Compositions and methods for inhibition of the JAK pathway | RIGEL PHARMACEUTICALS, INC. (US) | 2023-06-06 | — | — | US | claimed |
| WO-2023053030-A1 | AN IMPROVED PROCESS FOR PURIFICATION OF PROTEIN | KASHIV BIOSCIENCES, LLC (US) | 2023-04-06 | — | — | WO | claimed |
| US-10556942-B2 | Process for the purification of TNFR:Fc fusion protein | LUPIN LIMITED (IN) | 2020-02-11 | — | — | US | claimed |
| US-20170152298-A1 | PROCESS FOR THE PURIFICATION OF TNFR:FC FUSION PROTEIN | LUPIN LIMITED (IN) | 2017-06-01 | — | — | US | claimed |
| EP-3155009-A1 | PROCESS FOR THE PURIFICATION OF TNFR:FC FUSION PROTEIN | Lupin Limited (IN) | 2017-04-19 | — | — | EP | claimed |
| WO-2015189832-A1 | PROCESS FOR THE PURIFICATION OF TNFR:FC FUSION PROTEIN | LUPIN LIMITED (IN) | 2015-12-17 | — | — | WO | claimed |
| CN-1918127-B | New cyclocompound having 4-pyridylalkylthio group to which substituted or unsubstituted amino group is introduced | SANTEN PHARMACEUTICAL CO.,LTD. (JP) | 2012-02-15 | — | — | CN | claimed |
| CN-1918127-A | New cyclocompound having 4-pyridylalkylthio group to which sustituted or unsubstituted amino group is introduced | SANTEN PHARMACEUTICAL CO LTD (JP) | 2007-02-21 | — | — | CN | claimed |
| US-6946581-B2 | Bisphenol compound composition having excellent thermal stability | MITSUBISHI CHEMICAL CORPORATION (JP) | 2005-09-20 | — | — | US | claimed |
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| US-5614533-A | Substituted pipecolinic acid derivatives as HIV protease inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH, INC. (CA) | 1997-03-25 | — | — | US | claimed |
| US-5453438-A | Hydroxamic acid based collagenase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-09-26 | — | — | US | claimed |
| EP-0560269-B1 | Substituted pyrrolidine derivatives as HIV protease inhibitors | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-05-31 | — | — | EP | claimed |
| EP-0560268-B1 | Substituted pipecolinic acid derivatives as HIV protease inhibitors | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-01-04 | — | — | EP | claimed |
| US-5304604-A | Treating diseases involving tissue degradation, promoting wound healing | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-04-19 | — | — | US | claimed |
| WO-1993018003-A1 | SUBSTITUED PIPECOLINIC ACID DERIVATIVES AS HIV PROTEASE INHIBITORS | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-16 | — | — | WO | claimed |
| EP-0560269-A1 | Substituted pyrrolidine derivatives as HIV protease inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-15 | — | — | EP | claimed |
| EP-0560268-A1 | Substituted pipecolinic acid derivatives as HIV protease inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-15 | — | — | EP | claimed |
| EP-0175363-B1 | 4,5-DIHYDRO-3(2H)-PYRIDAZINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1990-01-17 | — | — | EP | claimed |
| US-4816454-A | CARDIOVASCULAR DISORDERS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1989-03-28 | — | — | US | claimed |