SCHEMBL11296307

SCHEMBL11296307

CC1(c2ccc([N+](=O)[O-])cc2)Nc2ccccc2S1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 1.00
▸ KMT2A Q03164 4/20 1.00
▸ NPC1 O15118 2/20 1.00
▸ RAB9A P51151 2/20 1.00
▸ SNCA P37840 5/20 0.48
▸ MAPT P10636 7/20 0.43
▸ APP P05067 4/20 0.41
▸ L3MBTL1 Q9Y468 3/20 0.40
▸ GFER P55789 1/20 0.40
▸ ALDH1A1 P00352 4/20 0.39
▸ LMNA P02545 3/20 0.39
▸ BCHE P06276 1/20 0.39
▸ TTR P02766 1/20 0.38
▸ LRRK2 Q5S007 1/20 0.38
▸ HPGD P15428 2/20 0.37
▸ KDM4E B2RXH2 2/20 0.37
▸ GAA P10253 1/20 0.37
▸ RUNX1 Q01196 1/20 0.37
▸ CBFB Q13951 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10739029 0.81 MEN1 (0.67) MEN1KMT2ANPC1RAB9ASNCA
Phenothiazine SCHEMBL27788701 0.73 SNCA (0.81) MEN1KMT2ANPC1RAB9ASNCA
SCHEMBL3234153 0.68 MEN1 (0.51) MEN1KMT2ANPC1RAB9ASNCA
SCHEMBL6276922 0.68 KMT2A (0.51) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL10883559 0.67 KMT2A (0.50) MEN1KMT2ANPC1RAB9ASNCA
SCHEMBL28414862 0.67 KMT2A (0.50) MEN1KMT2ANPC1RAB9ASNCA
SCHEMBL1641615 0.66 MEN1 (0.47) MEN1KMT2ANPC1RAB9ASNCA
SCHEMBL14535299 0.66 MEN1 (0.47) MEN1KMT2ANPC1RAB9ASNCA
SCHEMBL239724 0.65 SNCA (1.00) MEN1KMT2ANPC1RAB9ASNCA
SCHEMBL11293817 0.65 MEN1 (0.48) MEN1KMT2ANPC1RAB9ASNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003263-B1 A METHOD OF FORMING AN IMAGE, AND AN IMAGING ELEMENT FOR INHIBITING IMAGE FORMATION WITH COBALT (III) COMPLEXES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-09-29 — — EP disclosed
US-4273860-A INCLUDING A PHOTOINHIBITOR TO SUPPRESS DECOMPOSITION OF THE COBALT COMPLEX USING RADIATION OF WAVELENGTHS LONGER THAN 300NM; NEGATIVES AND POSITIVES EASTMAN KODAK COMPANY (US) 1981-06-16 — — US disclosed
EP-0003263-A1 A method of forming an image, and an imaging element for inhibiting image formation with cobalt (III) complexes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-08-08 — — EP disclosed
WO-1979000448-A1 INHIBITING IMAGE FORMATION WITH COBALT(III)COMPLEXES EASTMAN KODAK CO (US) 1979-07-26 — — WO disclosed
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