SCHEMBL239724

SCHEMBL239724

O=[N+]([O-])c1ccc2c(c1)Sc1ccccc1N2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 9/20 1.00
NOX1 Q9Y5S8 6/20 0.64
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
GAA P10253 3/20 0.55
MAPT P10636 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
BCHE P06276 2/20 0.55
ACHE P22303 2/20 0.55
CYP1A2 P05177 1/20 0.55
POLB P06746 1/20 0.55
CYP3A4 P08684 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
ALOX15 P16050 1/20 0.55
ALOX12 P18054 1/20 0.55
MAOA P21397 1/20 0.55
CNR1 P21554 1/20 0.55
PTGS1 P23219 1/20 0.55
SLC6A2 P23975 1/20 0.55
HTR2C P28335 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30769632 1.00 SNCA (1.00) SNCANOX1MEN1KMT2AGAA
SCHEMBL29625234 0.92 SNCA (0.84) SNCANOX1MEN1KMT2AMAPT
SCHEMBL1208092 0.92 SNCA (0.84) SNCANOX1MEN1KMT2AMAPT
SCHEMBL28091598 0.92 SNCA (0.86) SNCANOX1MEN1KMT2AGAA
SCHEMBL8941280 0.90 SNCA (0.82) SNCANOX1MEN1KMT2AGAA
Phenothiazine SCHEMBL27788701 0.90 SNCA (0.81) SNCANOX1MEN1KMT2AGAA
SCHEMBL29214094 0.89 SNCA (0.79) SNCANOX1MEN1KMT2AGAA
SCHEMBL30867073 0.89 SNCA (0.79) SNCANOX1MEN1KMT2AGAA
Dimethyl Sulfoxide SCHEMBL18398818 0.84 SNCA (0.72) SNCANOX1MEN1KMT2AMAPT
SCHEMBL14571431 0.84 SNCA (0.72) SNCANOX1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119463156-A Amphiphilic organic near-infrared thermal activation delayed fluorescence molecule and preparation method and application thereof 内蒙古大学 2025-02-18 CN claimed
US-20250376556-A1 Curable Epoxy Resin Compositions with High Glass Transition Tempature HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2025-12-11 US disclosed
US-12479810-B2 Phenothiazine compound, its preparation and use in rubber blends and vehicle tires, as ageing protectant, antioxidant, antiozonant and colorant CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2025-11-25 US disclosed
US-20250325557-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2025-10-23 US disclosed
US-12324810-B2 3, 7-diamino-10H-phenothiazine salts and their use WISTA LABORATORIES LTD. (SG) 2025-06-10 US disclosed
CN-116323786-B Phenothiazine compounds, their preparation and their use as age protectors, antioxidants, antiozonants and colorants in rubber blends and vehicle tires 大陆轮胎德国有限公司 2025-05-23 CN disclosed
CN-119463156-A Amphiphilic organic near-infrared thermal activation delayed fluorescence molecule and preparation method and application thereof 内蒙古大学 2025-02-18 CN disclosed
CN-119487097-A Curable epoxy resin composition with high glass transition temperature 亨斯迈先进材料美国有限责任公司 2025-02-18 CN disclosed
CN-119241469-A Photoinitiator, photopolymerization composition and application thereof 武汉尚赛光电科技有限公司 2025-01-03 CN disclosed
US-20240245700-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2024-07-25 US disclosed
EP-1233962-A2 NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE AS MEDICINES SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2002-08-28 EP disclosed
CN-1335841-A N- (iminomethyl) amine derivatives, their preparation, their use as medicaments and pharmaceutical compositions containing them SOD CONSEILS RECH APPLIC (FR) 2002-02-13 CN disclosed
WO-2001085677-A1 AMINO ACID DERIVATIVES AND THEIR USE AS MEDICINES SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2001-11-15 WO disclosed
EP-1115720-A2 NOVEL N-(IMINOMETHYL)AMINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2001-07-18 EP disclosed
WO-2001032654-A2 NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE AS MEDICINES SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2001-05-10 WO disclosed
WO-2000017191-A2 N-(IMINOMETHYL)AMINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2000-03-30 WO disclosed
EP-0517656-B1 Fire-protected polyimide composition CIBA GEIGY AG (CH) 1997-08-20 EP disclosed
US-5637387-A PREPOLYMER OF BISMALEIMIDE AND ALKENYLPHENOL STABILIZED WITH PHENOTHIAZINE OR DERIVATIVE THEREOF OR HYDROQUINONE CIBA-GEIGY CORPORATION (US) 1997-06-10 US disclosed
US-5240981-A Blend with alkenylphenol, tribromophenylmaleimide, free radical catalyst, and phenothiazine derivative CIBA-GEIGY CORPORATION (US) 1993-08-31 US disclosed
EP-0517656-A2 Fire-protected polyimide composition CIBA-GEIGY AG (CH) 1992-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325557-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP SNCA 673/4885NOX1 187/4885MEN1 2704/4885
US-12324810-B2 3, 7-diamino-10H-phenothiazine salts and their use PSEN1, PSEN2, APP SNCA 467/4885NOX1 347/4885MEN1 3093/4885
US-12479810-B2 Phenothiazine compound, its preparation and use in rubber blends and vehicle tires, as ageing protectant, antioxidant, antiozonant and colorant POT1, HTT, TERB1 SNCA 1201/4885NOX1 794/4885MEN1 2900/4885
US-20240245700-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP SNCA 467/4885NOX1 347/4885MEN1 3093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.