Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ADAMTS5 | Q9UNA0 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278729 | 0.88 | ACHE (0.47) | KMT2AMEN1NPC1RAB9AADAMTS5 | |
| SCHEMBL6277990 | 0.80 | ADAMTS5 (0.47) | KMT2AMEN1NPC1RAB9AADAMTS5 | |
| SCHEMBL6260436 | 0.80 | MECP2 (0.47) | KMT2AMEN1NPC1RAB9AADAMTS5 | |
| SCHEMBL6274347 | 0.79 | ADAMTS5 (0.47) | KMT2AMEN1NPC1RAB9AADAMTS5 | |
| SCHEMBL6275485 | 0.78 | MEN1 (0.48) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL6274203 | 0.73 | ALDH1A1 (0.49) | NPC1RAB9AADAMTS5ALDH1A1LMNA | |
| SCHEMBL6272309 | 0.72 | ADAMTS5 (0.38) | KMT2AMEN1NPC1RAB9AADAMTS5 | |
| SCHEMBL6277236 | 0.72 | ADAMTS5 (0.52) | NPC1RAB9AADAMTS5ALDH1A1LMNA | |
| SCHEMBL6387706 | 0.72 | ADAMTS5 (0.40) | KMT2AMEN1ADAMTS5ALDH1A1LMNA | |
| SCHEMBL6274028 | 0.70 | ADAMTS5 (0.75) | KMT2AMEN1ADAMTS5ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | claimed |