Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.45 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GGH | Q92820 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21826646 | 0.83 | PRMT1 (0.50) | FOLH1LMNAMEN1TSHRKMT2A | |
| SCHEMBL731378 | 0.79 | MMP2 (0.39) | CA12CA9 | |
| SCHEMBL17061026 | 0.79 | FOLH1 (0.39) | FOLH1NAALAD2LMNAMEN1HPGD | |
| SCHEMBL3087186 | 0.76 | FOLH1 (0.37) | FOLH1NAALAD2LMNAMEN1HPGD | |
| SCHEMBL9060867 | 0.75 | LMNA (0.43) | FOLH1NAALAD2LMNAMEN1HPGD | |
| SCHEMBL285956 | 0.72 | CA12 (0.33) | MEN1KMT2ACA12CA9 | |
| SCHEMBL17187190 | 0.72 | S1PR2 (0.40) | CA12CA9 | |
| SCHEMBL2991000 | 0.71 | FOLH1 (0.40) | FOLH1NAALAD2LMNAMEN1HPGD | |
| SCHEMBL5935325 | 0.71 | FOLH1 (0.41) | FOLH1NAALAD2LMNAMEN1HPGD | |
| SCHEMBL4320919 | 0.70 | LMNA (0.40) | FOLH1NAALAD2LMNAMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012194-B1 | PROCESS FOR THE PREPARATION OF N-CARBOXYALKYL-1-AMINOALKANE DIPHOSPHONIC ACIDS AND CARBOXYALKYLAMINO-PHENYL-METHANE DIPHOSPHONIC ACIDS | Benckiser-Knapsack GmbH (DE) | 1982-02-03 | — | — | EP | disclosed |
| US-4308147-A | Composition and treating aqueous solutions with N-carboxy alkyl amino alkane polyphosphonic acids and their alkali metal salts | BENCKISER-KNAPSACK GMBH (DE) | 1981-12-29 | — | — | US | disclosed |
| US-4307038-A | N-Carboxy alkyl amino alkane polyphosphonic acids | BENCKISER-KNAPSACK GMBH (DE) | 1981-12-22 | — | — | US | disclosed |