Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | BAX | Q07812 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297104 | 0.86 | ALDH1A1 (0.56) | TSHRALDH1A1ALOX15MEN1KMT2A | |
| SCHEMBL19620174 | 0.83 | CA4 (0.50) | LTA4HALDH1A1ALOX15CA1CA2 | |
| SCHEMBL8715862 | 0.77 | LTA4H (0.55) | LTA4HNR1H2BAXTSHRALDH1A1 | |
| SCHEMBL25862884 | 0.75 | LTA4H (0.60) | LTA4HNR1H2BAXTSHRALDH1A1 | |
| SCHEMBL11226988 | 0.73 | ALDH1A1 (0.58) | LTA4HNR1H2BAXTSHRALDH1A1 | |
| SCHEMBL11745214 | 0.73 | LTA4H (0.50) | LTA4HNR1H2BAXTSHRALDH1A1 | |
| SCHEMBL10760022 | 0.73 | ALDH1A1 (0.58) | LTA4HNR1H2BAXTSHRALDH1A1 | |
| SCHEMBL21118545 | 0.71 | LTA4H (0.55) | LTA4HNR1H2BAXTSHRPARP10 | |
| SCHEMBL9248118 | 0.71 | ALDH1A1 (0.56) | LTA4HNR1H2BAXTSHRALDH1A1 | |
| SCHEMBL11481229 | 0.71 | ALDH1A1 (0.42) | TSHRALDH1A1ALOX15SRD5A2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363894-A | Glass reinforced polyamide compositions having improved impact strengths | RHONE-POULENC INDUSTRIES (FR) | 1982-12-14 | — | — | US | disclosed |