Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CPA2 | P48052 | 1/20 | 0.38 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 5/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 5/20 | 0.33 |
| ▸ | MME | P08473 | 3/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.33 |
| ▸ | NMT2 | O60551 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | IL1RN | P18510 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alafosfalin SCHEMBL1582303 | 0.86 | DPP4 (0.48) | PAX8DPP4ANPEPDPP8DPP7 | |
| Alafosfalin SCHEMBL1582301 | 0.86 | DPP4 (0.48) | PAX8DPP4ANPEPDPP8DPP7 | |
| Alafosfalin SCHEMBL456724 | 0.86 | DPP4 (0.48) | PAX8DPP4ANPEPDPP8DPP7 | |
| Alafosfalin SCHEMBL11032329 | 0.86 | DPP4 (0.48) | PAX8DPP4ANPEPDPP8DPP7 | |
| SCHEMBL11303152 | 0.84 | METAP1 (0.42) | DPP4ANPEPDPP8DPP7LAP3 | |
| Alafosfalin SCHEMBL9619892 | 0.84 | DPP4 (0.47) | PAX8DPP4ANPEPDPP8DPP7 | |
| Alafosfalin SCHEMBL11297483 | 0.84 | DPP4 (0.47) | PAX8DPP4ANPEPDPP8DPP7 | |
| SCHEMBL30552905 | 0.79 | MME (0.51) | PAX8DPP4DPP8DPP7MME | |
| SCHEMBL30452082 | 0.79 | MME (0.51) | PAX8DPP4DPP8DPP7MME | |
| SCHEMBL11297402 | 0.79 | ANPEP (0.40) | DPP4ANPEPDPP8LAP3ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250085-A | PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | disclosed |