Alafosfalin

Alafosfalin

SCHEMBL11032329

C[C@H](N)C(=O)N[C@H](C)P(=O)(O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.48
LAP3 P28838 4/20 0.41
ANPEP P15144 5/20 0.41
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
CA9 Q16790 1/20 0.38
DPP8 Q6V1X1 1/20 0.38
DPP7 Q9UHL4 1/20 0.38
PAX8 Q06710 1/20 0.37
ERAP1 Q9NZ08 1/20 0.37
CTRB1 P17538 3/20 0.36
ALDH1A1 P00352 2/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alafosfalin SCHEMBL1582303 1.00 DPP4 (0.48) DPP4LAP3ANPEPCA12CA1
Alafosfalin SCHEMBL1582301 1.00 DPP4 (0.48) DPP4LAP3ANPEPCA12CA1
Alafosfalin SCHEMBL456724 1.00 DPP4 (0.48) DPP4LAP3ANPEPCA12CA1
Alafosfalin SCHEMBL9619892 0.98 DPP4 (0.47) DPP4LAP3ANPEPCA12CA1
Alafosfalin SCHEMBL11297483 0.98 DPP4 (0.47) DPP4LAP3ANPEPCA12CA1
SCHEMBL11299128 0.92 DPP4 (0.42) DPP4LAP3ANPEPCA12CA1
SCHEMBL18919534 0.92 DPP4 (0.42) DPP4LAP3ANPEPCA12CA1
SCHEMBL1582769 0.92 DPP4 (0.42) DPP4LAP3ANPEPCA12CA1
SCHEMBL1582242 0.92 DPP4 (0.42) DPP4LAP3ANPEPCA12CA1
SCHEMBL11296889 0.86 PAX8 (0.40) DPP4LAP3ANPEPDPP8DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146063-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-05-28 US disclosed
WO-2026107208-A1 COMPOSITIONS AND METHODS FOR TREATING MICROBIAL INFECTIONS THE METHODIST HOSPITAL (US) 2026-05-21 WO disclosed
US-20260124192-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING RNA VIRAL INFECTIONS MODEL MEDICINES INC (US) 2026-05-07 US disclosed
US-20260125426-A1 CYCLIC CELL-PENETRATING PEPTIDES AND USES THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-05-07 US disclosed
EP-3958767-B1 DEVICES FOR DELIVERING THERAPEUTIC MATERIALS TO THE INTERVERTEBRAL DISC WARSAW ORTHOPEDIC INC (US) 2026-04-22 EP disclosed
US-20260102384-A1 USE OF PIPENDOXIFENE FOR TREATING INFECTIONS OF DNA VIRUSES MODEL MEDICINES INC (US) 2026-04-16 US disclosed
US-12582455-B2 Bone material dispensing device WARSAW ORTHOPEDIC, INC. (US) 2026-03-24 US disclosed
US-20260070947-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-03-12 US disclosed
US-20260070948-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH CARGO OHIO STATE INNOVATION FOUNDATION (US) 2026-03-12 US disclosed
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 EP disclosed
US-20220160464-A1 SMART COMPOSITE WITH ANTIBIOFILM, MINERALIZING, AND ANTIINFECTION THERAPEUTIC EFFECTS TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2022-05-26 US disclosed
EP-3395273-B1 BONE MATERIAL DISPENSING APPARATUS AND METHODS WARSAW ORTHOPEDIC INC (US) 2022-05-04 EP disclosed
EP-3308719-B1 EXPANDABLE DEVICE FOR TISSUE COLLECTION FROM AN AERODIGESTIVE BODY LUMEN ADN INT LLC (US) 2022-03-30 EP disclosed
EP-3965799-A1 COMPOSITIONS AND SYNERGISTIC METHODS FOR TREATING INFECTIONS Bioaegis Therapeutics Inc. (US) 2022-03-16 EP disclosed
WO-2022049149-A1 CHEWABLE FORMULATIONS ELANCO TIERGESUNDHEIT AG (CH) 2022-03-10 WO disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
EP-3946489-A1 SMART COMPOSITE WITH ANTIBIOFILM, MINERALIZING, AND ANTIINFECTION THERAPEUTIC EFFECTS Temple University - Of The Commonwealth System of Higher Education (US) 2022-02-09 EP disclosed
WO-2022020752-A1 LIQUID CRYSTAL SCAFFOLDS AND USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-01-27 WO disclosed
US-4431438-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1984-02-14 US disclosed
EP-0010067-A2 Process for influencing plant growth CIBA-GEIGY AG (CH) 1980-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260102384-A1 USE OF PIPENDOXIFENE FOR TREATING INFECTIONS OF DNA VIRUSES ESR1, VDR, POLL DPP4 73/4885LAP3 1480/4885ANPEP 637/4885
US-20260146063-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, SLC7A1, SLC6A15 DPP4 523/4885LAP3 50/4885ANPEP 16/4885
US-20260125426-A1 CYCLIC CELL-PENETRATING PEPTIDES AND USES THEREOF SLC7A1, TAP1, SLC7A5 DPP4 1103/4885LAP3 385/4885ANPEP 54/4885
US-20260070947-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS SLC7A1, SLC38A7, SLC6A19 DPP4 710/4885LAP3 139/4885ANPEP 57/4885
US-20260070948-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH CARGO SLC7A1, SLC38A7, SLC6A19 DPP4 994/4885LAP3 130/4885ANPEP 77/4885
US-20260124192-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING RNA VIRAL INFECTIONS SARS1, NSUN2, NSUN3 DPP4 150/4885LAP3 2134/4885ANPEP 812/4885
US-12582455-B2 Bone material dispensing device BMP2, BMP4, BMP1 DPP4 1567/4885LAP3 884/4885ANPEP 2577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.