Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.40 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11293584 | 0.83 | LPAR1 (0.49) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL8322731 | 0.83 | USP2 (0.46) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL11293582 | 0.83 | LPAR1 (0.49) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL8677401 | 0.81 | USP2 (0.44) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL7591541 | 0.81 | USP2 (0.43) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL1685011 | 0.80 | USP2 (0.43) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL4204833 | 0.77 | LPAR1 (0.68) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL4879843 | 0.77 | LPAR1 (0.68) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL4294185 | 0.77 | LPAR1 (0.68) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL8636551 | 0.77 | LPAR1 (0.68) | USP2LPAR1LPAR3LPAR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202760-B1 | PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY | ALNYLAM PHARMACEUTICALS INC (US) | 2019-08-21 | — | — | EP | disclosed |
| US-9999673-B2 | PEGylated lipids and their use for drug delivery | ALNYLAM PHARMACEUTICALS, INC. (US) | 2018-06-19 | — | — | US | disclosed |
| EP-3202760-A1 | PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY | Alnylam Pharmaceuticals, Inc. (US) | 2017-08-09 | — | — | EP | disclosed |
| EP-2663548-B1 | PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY | ALNYLAM PHARMACEUTICALS INC (US) | 2017-04-05 | — | — | EP | disclosed |
| EP-2663548-A1 | PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY | Alnylam Pharmaceuticals, Inc. (US) | 2013-11-20 | — | — | EP | disclosed |
| WO-2012099755-A1 | PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-07-26 | — | — | WO | disclosed |