Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297008 | 0.80 | USP2 (0.47) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL8322731 | 0.79 | USP2 (0.46) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL11293582 | 0.79 | LPAR1 (0.49) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL11293584 | 0.79 | LPAR1 (0.49) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL8677401 | 0.77 | USP2 (0.44) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL7591541 | 0.77 | USP2 (0.43) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL4879843 | 0.73 | LPAR1 (0.68) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL4204833 | 0.73 | LPAR1 (0.68) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL4294185 | 0.73 | LPAR1 (0.68) | USP2LPAR1LPAR3LPAR2HTT | |
| SCHEMBL8636551 | 0.73 | LPAR1 (0.68) | USP2LPAR1LPAR3LPAR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181742-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation | 2023-06-15 | — | — | US | claimed |
| US-20200061197-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation | 2020-02-27 | — | — | US | claimed |
| US-10406237-B2 | Amine-containing transfection reagents and methods for making and using same | LIFE TECHNOLOLGIES CORPORATION (US) | 2019-09-10 | — | — | US | claimed |
| EP-3470395-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation (US) | 2019-04-17 | — | — | EP | claimed |
| EP-2640700-B1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | LIFE TECHNOLOGIES CORP (US) | 2018-10-31 | — | — | EP | claimed |
| US-20180200374-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation | 2018-07-19 | — | — | US | claimed |
| US-9901642-B2 | Amine-containing transfection reagents and methods for making and using same | Life Technologies Corporation (US) | 2018-02-27 | — | — | US | claimed |
| US-20230181742-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation | 2023-06-15 | — | — | US | disclosed |
| US-20200061197-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation | 2020-02-27 | — | — | US | disclosed |
| US-10406237-B2 | Amine-containing transfection reagents and methods for making and using same | LIFE TECHNOLOLGIES CORPORATION (US) | 2019-09-10 | — | — | US | disclosed |
| EP-3470395-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-2640700-B1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | LIFE TECHNOLOGIES CORP (US) | 2018-10-31 | — | — | EP | disclosed |
| US-20180200374-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation | 2018-07-19 | — | — | US | disclosed |
| EP-2216415-B2 | Methods for preparing short RNA molecules | LIFE TECHNOLOGIES CORP (US) | 2017-01-04 | — | — | EP | disclosed |
| EP-1660631-B1 | COMPOSITIONS AND METHODS FOR PURIFYING SHORT RNA MOLECULES | LIFE TECHNOLOGIES CORP (US) | 2013-04-24 | — | — | EP | disclosed |
| EP-2216415-B1 | Methods for preparing short RNA molecules | LIFE TECHNOLOGIES CORP (US) | 2012-12-26 | — | — | EP | disclosed |
| EP-2311994-A1 | Compositions and methods for preparing short RNA molecules and other nucleic acids | Life Technologies Corporation (US) | 2011-04-20 | — | — | EP | disclosed |
| EP-2216415-A1 | Compositions and methods for preparing short RNA molecules and other nucleic acids | Life Technologies Corporation (US) | 2010-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10406237-B2 | Amine-containing transfection reagents and methods for making and using same | SNRPA, NUDT21, SOAT2 | USP2 3972/4885LPAR1 501/4885LPAR3 559/4885 |
| US-20230181742-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | SNRPA, NUDT21, SOAT2 | USP2 3972/4885LPAR1 501/4885LPAR3 559/4885 |
| US-20200061197-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | SNRPA, NUDT21, SOAT2 | USP2 3972/4885LPAR1 501/4885LPAR3 559/4885 |
| US-20180200374-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | SNRPA, NUDT21, SOAT2 | USP2 3972/4885LPAR1 501/4885LPAR3 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.