SCHEMBL11297014

SCHEMBL11297014

O=P(O)(O)CS.Oc1ccccc1CCCS.Oc1ccccc1CCS

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.44
MPO P05164 5/20 0.44
SLC6A4 P31645 2/20 0.44
TAAR1 Q96RJ0 1/20 0.43
FOLH1 Q04609 1/20 0.42
TSHR P16473 1/20 0.41
HSPA5 P11021 1/20 0.39
AKR1B1 P15121 1/20 0.39
GAA P10253 1/20 0.38
KEAP1 Q14145 1/20 0.37
IAPP P10997 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10540048 0.86 TAAR1 (0.56) MGLLMPOSLC6A4TAAR1TSHR
SCHEMBL2408473 0.82 TAAR1 (0.60) MPOSLC6A4TAAR1FOLH1TSHR
SCHEMBL10751399 0.80 TAAR1 (0.54) MGLLMPOSLC6A4TAAR1TSHR
Phosphoric Acid SCHEMBL16266190 0.74 TSHR (0.60) MGLLMPOSLC6A4TAAR1TSHR
SCHEMBL4967651 0.73 TAAR1 (0.65) MGLLMPOSLC6A4TAAR1TSHR
SCHEMBL3800530 0.73 TAAR1 (0.65) MGLLMPOSLC6A4TAAR1TSHR
Phosphoric Acid SCHEMBL538743 0.72 TSHR (0.58) MGLLTSHR
SCHEMBL8401990 0.71 MGLL (0.66) MGLLMPOSLC6A4TAAR1TSHR
SCHEMBL8398317 0.71 MGLL (0.66) MGLLMPOSLC6A4TAAR1TSHR
SCHEMBL10438887 0.71 TAAR1 (0.62) MGLLMPOSLC6A4TAAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0062474-A1 Photosensitive compositions containing a polyene E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-10-13 EP disclosed