Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18816145 | 0.79 | TDP1 (0.48) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL3959829 | 0.78 | TDP1 (0.54) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL28015802 | 0.78 | TDP1 (0.58) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL5248130 | 0.78 | TDP1 (0.58) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL3115667 | 0.78 | ALDH1A1 (0.54) | TDP1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL2975355 | 0.77 | TDP1 (0.47) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL7801282 | 0.77 | ALDH1A1 (0.51) | TDP1TSHRSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL272154 | 0.76 | ERN1 (0.57) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL5783218 | 0.74 | TDP1 (0.54) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 | |
| SCHEMBL8361517 | 0.74 | TDP1 (0.58) | TDP1TSHRSMN1; SMN2GPR35HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067954-A2 | Organic photoconductive compositions for electrophotography | KABUSHIKI KAISHA TOSHIBA (JP) | 1982-12-29 | — | — | EP | disclosed |