SCHEMBL7801282

SCHEMBL7801282

CC[CH]c1c([N+](=O)[O-])ccc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.51
HPRT1 P00492 1/20 0.49
TSHR P16473 2/20 0.46
MAPT P10636 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
TDP1 Q9NUW8 3/20 0.42
CASP6 P55212 1/20 0.41
CTSB P07858 1/20 0.41
LMNA P02545 2/20 0.41
HPGD P15428 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
MITF O75030 1/20 0.41
HSP90AA1 P07900 1/20 0.41
PKM P14618 1/20 0.41
MAPK1 P28482 1/20 0.41
TLR9 Q9NR96 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8153136 0.83 ALDH1A1 (0.55) ALDH1A1HPRT1TSHRMAPTMEN1
SCHEMBL6414469 0.83 ALDH1A1 (0.55) ALDH1A1HPRT1TSHRMAPTMEN1
SCHEMBL5175572 0.83 ALDH1A1 (0.58) ALDH1A1HPRT1TSHRMAPTTDP1
SCHEMBL31338905 0.83 ALDH1A1 (0.58) ALDH1A1HPRT1TSHRMAPTTDP1
SCHEMBL8153134 0.80 ALDH1A1 (0.55) ALDH1A1HPRT1TSHRMAPTMEN1
SCHEMBL11297088 0.77 TDP1 (0.54) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL7882450 0.75 ALDH1A1 (0.45) ALDH1A1HPRT1TSHRMEN1KMT2A
SCHEMBL7877612 0.75 ALDH1A1 (0.47) ALDH1A1HPRT1TSHRMAPTMEN1
Alcohol SCHEMBL28601219 0.74 CASP6 (0.57) ALDH1A1HPRT1TSHRMAPTMEN1
SCHEMBL6263857 0.74 ALDH1A1 (0.51) ALDH1A1HPRT1TSHRMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0576199-B1 Fungicidal and herbicidal triazoles ROHM & HAAS (US) 2001-08-01 EP disclosed
EP-0711775-A1 1,2,4-triazole alkylation ROHM AND HAAS COMPANY (US) 1996-05-15 EP disclosed
US-5510493-A Process for alkylation with triazoles ROHM AND HAAS COMPANY (US) 1996-04-23 US disclosed
US-5397768-A 1,2,4-triazoles ROHM AND HAAS COMPANY (US) 1995-03-14 US disclosed
EP-0576199-A2 Fungicidal and herbicidal triazoles ROHM AND HAAS COMPANY (US) 1993-12-29 EP disclosed
US-5264415-A 1,2,4-Triazole derivatives ROHM AND HAAS COMPANY (US) 1993-11-23 US disclosed
US-5192783-A Fungicides for plants ROHM AND HAAS COMPANY (US) 1993-03-09 US disclosed
US-4366165-A 1 and 4-Arylcyanoalkyl-1,2,4-triazoles and fungicidal use ROHM AND HAAS COMPANY (US) 1982-12-28 US disclosed