Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27801663 | 0.87 | TSHR (0.55) | TDP1GPR35ALDH1A1KDM4ETSHR | |
| SCHEMBL27780340 | 0.87 | MAPT (0.43) | TDP1GPR35ALDH1A1KDM4ETSHR | |
| SCHEMBL27780320 | 0.87 | ALDH1A1 (0.52) | TDP1GPR35ALDH1A1KDM4ETSHR | |
| SCHEMBL5781293 | 0.83 | TDP1 (0.54) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8730292 | 0.81 | TDP1 (0.43) | TDP1GPR35ALDH1A1KDM4ETSHR | |
| SCHEMBL1802353 | 0.79 | ALDH1A1 (0.62) | TDP1ALDH1A1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL7159890 | 0.79 | GPR35 (0.54) | TDP1GPR35ALDH1A1KDM4ETSHR | |
| SCHEMBL17319424 | 0.79 | TDP1 (0.54) | TDP1GPR35ALDH1A1KDM4ETSHR | |
| SCHEMBL6118566 | 0.79 | TDP1 (0.50) | TDP1GPR35ALDH1A1KDM4ETSHR | |
| SCHEMBL5248139 | 0.78 | TDP1 (0.58) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067954-A2 | Organic photoconductive compositions for electrophotography | KABUSHIKI KAISHA TOSHIBA (JP) | 1982-12-29 | — | — | EP | disclosed |