Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25474471 | 0.84 | TEAD1 (0.55) | KMT2AEPHX2 | |
| SCHEMBL19613180 | 0.83 | OPRM1 (0.45) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL19613178 | 0.83 | OPRM1 (0.45) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL19613179 | 0.83 | OPRM1 (0.45) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL19613987 | 0.83 | OPRM1 (0.45) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL19613986 | 0.83 | OPRM1 (0.45) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL28543009 | 0.78 | TSHR (0.56) | ALDH1A1DRD4KMT2ATSHRCYP3A4 | |
| SCHEMBL19633997 | 0.78 | OPRM1 (0.57) | OPRM1OPRD1OPRK1OPRL1BRD4 | |
| SCHEMBL9594799 | 0.78 | LTA4H (0.52) | LTA4HDRD2DRD3KMT2ACCR1 | |
| SCHEMBL22590200 | 0.77 | BACE1 (0.43) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052311-A1 | 1-((Benzoylphenyl) - lower-alkyl) piperidines and carbinol analogs and preparation thereof | STERLING DRUG INC. (US) | 1982-05-26 | — | — | EP | disclosed |