Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11302453 | 0.88 | HDAC8 (0.37) | HDAC8RXRARXRBABCB1HPGD | |
| SCHEMBL11293873 | 0.88 | TAS1R3 (0.38) | MAPTABCB1HPGDTSHR | |
| SCHEMBL11304921 | 0.80 | HDAC8 (0.46) | HDAC8MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL11300475 | 0.79 | HDAC8 (0.34) | HDAC8LMNATSHR | |
| SCHEMBL11296873 | 0.78 | TDP1 (0.52) | MAPTLMNASMN1; SMN2HPGDTSHR | |
| SCHEMBL11211541 | 0.78 | SLC6A2 (0.39) | MAPTABCB1HPGDTSHRF10 | |
| SCHEMBL11407028 | 0.76 | TP53 (0.39) | MAPTLMNASMN1; SMN2ABCB1HPGD | |
| SCHEMBL11398910 | 0.76 | SMN1; SMN2 (0.51) | LMNASMN1; SMN2HPGDTSHR | |
| SCHEMBL11295563 | 0.76 | HDAC8 (0.33) | HDAC8 | |
| SCHEMBL11298187 | 0.75 | TAS1R3 (0.40) | LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261732-A | Alkyl and alkoxyalkyl N-3-alkyl and N-3,5-dialkylbenzoyl-N-isopropylaminoacetate herbicides | PPG INDUSTRIES, INC. (US) | 1981-04-14 | — | — | US | disclosed |