Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | BAX | Q07812 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291672 | 0.93 | CA1 (0.35) | CA1CA2CA12CA7CA13 | |
| SCHEMBL980809 | 0.77 | TTR (0.45) | PDE4BPDE4APDE4CPDE4DLTA4H | |
| SCHEMBL711861 | 0.77 | CA1 (0.44) | CA1CA2CA12CA7CA13 | |
| SCHEMBL11292325 | 0.77 | PDE4B (0.38) | CA1CA2CA12CA7CA13 | |
| SCHEMBL11297225 | 0.75 | ACLY (0.40) | POLBSMN1; SMN2KDM4EHSD17B10MEN1 | |
| SCHEMBL9459889 | 0.73 | HTT (0.41) | HTTPOLBGAAGFERALDH1A1 | |
| SCHEMBL9460314 | 0.73 | POLB (0.39) | CA1CA2HTTPOLBGAA | |
| SCHEMBL6735347 | 0.73 | CA1 (0.41) | CA1CA2CA12CA7CA13 | |
| SCHEMBL11290834 | 0.73 | POLB (0.46) | CA1CA2CA12CA7CA13 | |
| SCHEMBL983374 | 0.70 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356325-A | Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-10-26 | — | — | US | claimed |