SCHEMBL6735347

SCHEMBL6735347

Nc1ccc(S(=O)(=O)c2ccc(N)c(O)c2Oc2ccccc2)c(Oc2ccccc2)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA12 O43570 1/20 0.41
CA7 P43166 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
GAA P10253 2/20 0.40
CA9 Q16790 2/20 0.39
SOS1 Q07889 1/20 0.39
CDC25B P30305 1/20 0.37
LTA4H P09960 2/20 0.36
NR1H2 P55055 1/20 0.36
BAX Q07812 1/20 0.36
MAOA P21397 1/20 0.36
HTR6 P50406 1/20 0.36
SLC7A11 Q9UPY5 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HTT P42858 1/20 0.36
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3272221 0.83 CA1 (0.42) CA1CA2CA12CA7CA13
SCHEMBL30618213 0.83 CA1 (0.42) CA1CA2CA12CA7CA13
SCHEMBL6741091 0.81 CDC25B (0.41) CA1CA2CA12CA7CA13
SCHEMBL461322 0.78 GAA (0.53) CA1CA2CA12CA7CA13
SCHEMBL8772881 0.78 GAA (0.53) CA1CA2CA12CA7CA13
SCHEMBL1662788 0.76 HTR6 (0.50) CA1CA2CA12CA7CA13
SCHEMBL502558 0.76 GAA (0.40) CA1CA2CA12CA7CA13
SCHEMBL711861 0.75 CA1 (0.44) CA1CA2CA12CA7CA13
SCHEMBL6735345 0.74 ADORA2A (0.44) CA1CA2CA9SOS1SLC7A11
SCHEMBL11297221 0.73 CA1 (0.40) CA1CA2CA12CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686106-B2 POLYIMIDESILOXANE COPOLYMERS UBE INDUSTRIES, LTD. (JP) 2004-02-03 US disclosed
US-20020001763-A1 Photosensitive resin compositions, insulating films, and processes for formation of the films UBE INDUSTRIES, LTD. 2002-01-03 US disclosed
US-5643986-A STORAGE STABLE, PROTECTIVE FILMS UBE INDUSTRIES, LTD. (JP) 1997-07-01 US disclosed