SCHEMBL1129728

SCHEMBL1129728

CCCCCCCCCCCCCCCCCCc1ccc(O)c(C(=O)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 2/20 1.00
PPARA Q07869 2/20 0.77
LCK P06239 2/20 0.63
PPARG P37231 1/20 0.62
STAT3 P40763 1/20 0.59
MCL1 Q07820 1/20 0.59
KLKB1 P03952 1/20 0.59
CTSB P07858 1/20 0.59
MMP9 P14780 1/20 0.59
DNMT1 P26358 1/20 0.59
DNMT3B Q9UBC3 1/20 0.59
DNMT3L Q9UJW3 1/20 0.59
DNMT3A Q9Y6K1 1/20 0.59
RARB P10826 4/20 0.57
RARA P10276 1/20 0.57
RARG P13631 1/20 0.57
EGFR P00533 1/20 0.55
PTPN11 Q06124 1/20 0.54
PTPRO Q16827 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27792578 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL29987416 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL3220025 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL221446 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL1373683 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL7803836 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL7575009 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL2529442 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL21389644 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL28044999 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3081186-A None JP disclosed
US-20240400932-A1 SPIRO COMPOUND AS DETERGENT ADDITIVE IN LUBRICANTS FOR MARINE ENGINES TOTALENERGIES ONETECH (FR) 2024-12-05 US disclosed
CN-118369406-A Spiro compounds as detergent additives in marine engine lubricants 道达尔能源万泰克公司 2024-07-19 CN disclosed
CN-118355097-A Lubricating composition for preventing or reducing abnormal combustion in engine 道达尔能源万泰克公司 2024-07-16 CN disclosed
CN-118339264-A Spiro compounds as detergent additives in lubricants intended for motorized systems 道达尔能源万泰克公司 2024-07-12 CN disclosed
EP-2954373-B1 CHEMICAL COATING FOR A LASER-MARKABLE MATERIAL FUJIFILM HUNT CHEMICALS US INC (US) 2019-04-24 EP disclosed
EP-2954373-A1 CHEMICAL COATING FOR A LASER-MARKABLE MATERIAL Fujifilm Hunt Chemicals US, Inc. (US) 2015-12-16 EP disclosed
WO-2014124052-A1 CHEMICAL COATING FOR A LASER-MARKABLE MATERIAL FUJIFILM HUNT CHEMICALS, INC. (US) 2014-08-14 WO disclosed
US-20130216947-A1 CHEMICAL COATING COMPOSITION FOR FORMING A LASER-MARKABLE MATERIAL AND A LASER-MARKABLE MATERIAL FUJIFILM HUNT CHEMICALS U.S.A., INC. 2013-08-22 US disclosed
US-8349766-B2 Thermosensitive recording material FUJIFILM CORPORATION (JP) 2013-01-08 US disclosed
EP-0334606-A2 Heat-sensitive recording sheet materials FUJI PHOTO FILM CO., LTD. (JP) 1989-09-27 EP disclosed
US-4870048-A COLORFAST IMAGE, LIGHT RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1989-09-26 US disclosed
US-4839332-A AMINO-SUBSTITUTED FLUORENE AND ACID; DISCOLORATION INHIBITON, CHEMICAL RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1989-06-13 US disclosed
US-4835133-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-30 US disclosed
US-4833118-A COLOR DEVELOPERS, SUBBING LAYERS, AROMATIC ESTERS OR CARBONATES FUJI PHOTO FILM CO., LTD. (JP) 1989-05-23 US disclosed
US-4808566-A COLORLESS DYE IS DIMER OF 3-(4-SUBSTITUTED AMINOARYL)-3-(SUBSTITUTED INDOL-3-YL) PHTHALIDE FUJI PHOTO FILM CO., LTD. (JP) 1989-02-28 US disclosed
EP-0275203-A2 Heat-sensitive recording material containing color forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-07-20 EP disclosed
EP-0262810-A2 Sheet recording material containing dye-forming components Fuji Photo Film Co., Ltd. (JP) 1988-04-06 EP disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed
EP-0124905-B1 PROTEASE INHIBITORS G.D. Searle & Co. (US) 1986-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400932-A1 SPIRO COMPOUND AS DETERGENT ADDITIVE IN LUBRICANTS FOR MARINE ENGINES DEGS1, PKD1, SAV1 KAT8 1387/4885PPARA 261/4885LCK 2378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.