SCHEMBL221446

SCHEMBL221446

CCCCCCCCc1ccc(O)c(C(=O)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 2/20 1.00
PPARA Q07869 2/20 0.77
LCK P06239 2/20 0.63
PPARG P37231 1/20 0.62
STAT3 P40763 1/20 0.59
MCL1 Q07820 1/20 0.59
KLKB1 P03952 1/20 0.59
CTSB P07858 1/20 0.59
MMP9 P14780 1/20 0.59
DNMT1 P26358 1/20 0.59
DNMT3B Q9UBC3 1/20 0.59
DNMT3L Q9UJW3 1/20 0.59
DNMT3A Q9Y6K1 1/20 0.59
RARB P10826 4/20 0.57
RARA P10276 1/20 0.57
RARG P13631 1/20 0.57
EGFR P00533 1/20 0.55
PTPN11 Q06124 1/20 0.54
PTPRO Q16827 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27792578 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL29987416 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL1129728 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL3220025 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL1373683 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL7803836 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL7575009 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL2529442 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL21389644 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3
SCHEMBL28044999 1.00 KAT8 (1.00) KAT8PPARALCKPPARGSTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144729-A1 A CLEANSING COMPOSITION L'OREAL (FR) 2026-05-28 US claimed
EP-4611719-A1 A CLEANSING COMPOSITION L'OREAL (FR) 2025-09-10 EP claimed
CN-120076784-A Cleaning composition 莱雅公司 2025-05-30 CN claimed
WO-2024092386-A1 A CLEANSING COMPOSITION L'OREAL (FR) 2024-05-10 WO claimed
US-8974804-B2 Composition in the form of an oil-in-water emulsion and uses thereof L'OREAL (FR) 2015-03-10 US claimed
US-20120301414-A1 COMPOSITION IN THE FORM OF AN OIL-IN-WATER EMULSION AND USES THEREOF L'OREAL (FR) 2012-11-29 US claimed
WO-2011047422-A1 ANTI-ACNE COMPOSITION AND USE THEREOF CHEMEQ LTD (AU) 2011-04-28 WO claimed
EP-1415645-B1 Composition in the form of an oil-in-water emulsion and its cosmetic uses OREAL (FR) 2007-10-03 EP claimed
EP-1029587-B1 Nanocapsules based on poly(alkylene adipate), their fabrication process, cosmetic and dermatological compositions containing them OREAL (FR) 2005-06-08 EP claimed
CN-1197559-C Nano-microcapsules based on aqueous dispersion anionic polymer its producing process and cosmetic composition OREAL (FR) 2005-04-20 CN claimed
EP-0987011-B1 Cosmetic and/or dermatological composition containing salicylic acid or its derivatives and its use OREAL (FR) 2002-07-17 EP claimed
US-6391863-B1 SKIN DISORDERS; AGING RESISTANCE L'OREAL (FR) 2002-05-21 US claimed
US-6379683-B1 LIPID CORE ENCAPSULATED WITH POLYMER L'OREAL (FR) 2002-04-30 US claimed
EP-1034839-B1 Nanocapsules based on dendritic polymers OREAL (FR) 2001-10-24 EP claimed
US-6281203-B1 ESTER OF A FATTY ACID AND GLUCOSE AND/OR ALKYLGLUCOSE, AND AN OXYETHYLENATED ETHER OF A FATTY ACID ESTER OF GLUCOSE AND/OR ALKYLGLUCOSE. L'OREAL (FR) 2001-08-28 US claimed
CN-1258500-A Nano-microcapsules based on aqueous dispersion anionic polymer its producing process and cosmetic composition OREAL (FR) 2000-07-05 CN claimed
CN-1258499-A Nano-microcapsules based on poly (alkyleneadipate) its producing process and its cosmetic composition OREAL (FR) 2000-07-05 CN claimed
EP-0765658-B1 Use of salicylic acid derivatives for the treatment of striae OREAL (FR) 1997-11-19 EP claimed
EP-0336812-B1 ASSOCIATION OF PYRIMIDINE DERIVATIVES AND UREA AND/OR ALLANTOIN DERIVATIVES TO INDUCE AND STIMULATE HAIR GROWTH AND TO REDUCE HAIR LOSS L'OREAL (FR) 1992-08-26 EP claimed
US-4372583-A Chromogenic copy system and method VASSILIADES ANTHONY E 1983-02-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120301414-A1 COMPOSITION IN THE FORM OF AN OIL-IN-WATER EMULSION AND USES THEREOF PLOD3, CUTA, LOXL1 KAT8 1397/4885PPARA 183/4885LCK 3123/4885
US-20260144729-A1 A CLEANSING COMPOSITION SMURF1, CUTA, S100B KAT8 1409/4885PPARA 1567/4885LCK 4514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.