SCHEMBL1129732

SCHEMBL1129732

CCCCCCCCCCCCS(=O)(=O)c1ccc(O)c(C(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 2/20 0.61
ALDH1A1 P00352 3/20 0.53
HPGD P15428 2/20 0.53
HSD17B10 Q99714 2/20 0.53
KDM4E B2RXH2 1/20 0.53
THRB P10828 3/20 0.50
S1PR3 Q99500 1/20 0.50
PPARA Q07869 1/20 0.50
ALOX15 P16050 1/20 0.48
SERPINE1 P05121 1/20 0.48
PTPN11 Q06124 1/20 0.47
PTPRO Q16827 1/20 0.47
THRA P10827 1/20 0.47
STAT3 P40763 4/20 0.46
CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10347259 1.00 KAT8 (0.61) KAT8ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL9379520 0.94 KAT8 (0.56) KAT8ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL10673351 0.89 PPARA (0.61) KAT8THRBS1PR3PPARASERPINE1
SCHEMBL20503359 0.83 RARB (0.56) ALDH1A1THRBS1PR3PPARATHRA
SCHEMBL29501631 0.82 ALDH1A1 (0.55) KAT8ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL4419062 0.82 ALDH1A1 (0.55) KAT8ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL8962184 0.82 THRB (0.48) KAT8ALDH1A1THRBS1PR3PPARA
SCHEMBL7153996 0.82 SERPINE1 (0.63) ALDH1A1THRBSERPINE1THRACA2
SCHEMBL9187857 0.81 PTPN11 (0.54) KAT8S1PR3PTPN11
SCHEMBL9187777 0.81 PTPN11 (0.54) KAT8S1PR3PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283287-B2 Thermosensitive recording material RICOH COMPANY, LTD. (JP) 2012-10-09 US disclosed
EP-2036737-B1 Thermosensitive recording material RICOH CO LTD (JP) 2011-02-16 EP disclosed
US-20090075817-A1 THERMOSENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2009-03-19 US disclosed
EP-2036737-A1 Thermosensitive recording material Ricoh Company, Ltd. (JP) 2009-03-18 EP disclosed
EP-0482668-B1 HEAT SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1993-08-04 EP disclosed
US-5187143-A Thermographic mixture of basic leuco dye and color developer comprising a zinc salt of terephthaldehydic acid or a composite salt also containing an aromatic acid KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-02-16 US disclosed
EP-0262810-B1 SHEET RECORDING MATERIAL CONTAINING DYE-FORMING COMPONENTS Fuji Photo Film Co., Ltd. (JP) 1992-12-09 EP disclosed
EP-0482668-A1 Heat sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-04-29 EP disclosed
US-4939132-A Novel 5-alkylsulfonylsalicylanilides and microbiocidal compositions for controlling the growth of microorganisms THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1990-07-03 US disclosed
EP-0198366-B1 NOVEL 5-ALKYLSULFONYLSALICYLANLIDES AND MICROBIOCIDAL COMPOSITIONS FOR CONTROLLING THE GROWTH OF MICROORGANISMS THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1990-05-09 EP disclosed
US-4920091-A CONTAINING SALICYLIC ACID DERIVATIVE AS ELECTRON ACCEPTING COLOR DEVELOPER; STABLE IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1990-04-24 US disclosed
US-4918047-A CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
US-4808566-A COLORLESS DYE IS DIMER OF 3-(4-SUBSTITUTED AMINOARYL)-3-(SUBSTITUTED INDOL-3-YL) PHTHALIDE FUJI PHOTO FILM CO., LTD. (JP) 1989-02-28 US disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed
EP-0198366-A1 Novel 5-alkylsulfonylsalicylanlides and microbiocidal compositions for controlling the growth of microorganisms THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1986-10-22 EP disclosed