Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 14/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10112571 | 0.78 | NISCH (0.60) | NISCHHTR1DHTR1B | |
| SCHEMBL4383292 | 0.74 | NISCH (0.70) | NISCHHTR1D | |
| SCHEMBL31552847 | 0.71 | NISCH (0.46) | NISCHHTR1D | |
| SCHEMBL22743021 | 0.71 | NISCH (0.46) | NISCHHTR1D | |
| SCHEMBL30801520 | 0.69 | NISCH (0.51) | NISCH | |
| SCHEMBL11153041 | 0.69 | MC4R (0.45) | NISCH | |
| SCHEMBL12765025 | 0.68 | NISCH (0.53) | NISCH | |
| SCHEMBL4383375 | 0.68 | NISCH (0.50) | NISCH | |
| SCHEMBL11516541 | 0.67 | NISCH (0.66) | NISCH | |
| SCHEMBL12362313 | 0.67 | NISCH (0.50) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629463-B2 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-08 | — | — | US | disclosed |
| US-20080132524-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | CLARK DAVID ALAN | 2008-06-05 | — | — | US | disclosed |
| US-7375232-B2 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-05-20 | — | — | US | disclosed |
| EP-1417204-B1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | DU PONT (US) | 2006-01-18 | — | — | EP | disclosed |
| US-20040242645-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132524-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | AOC2, DDT, CBR3 | NISCH 53/4885HTR1D 1718/4885HTR1B 2425/4885 |
| US-20040242645-A1 | Ortho-heterocyclic substituted aryl amides for controlling invertebrate pests | AOC2, OLA1, AOC3 | NISCH 17/4885HTR1D 1962/4885HTR1B 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.