Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 11/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297884 | 1.00 | CA12 (0.48) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL2222204 | 0.83 | CA12 (0.58) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL9113110 | 0.72 | CA12 (0.49) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL9113097 | 0.72 | CA12 (0.49) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL11298525 | 0.71 | ALOX5 (0.46) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL11298524 | 0.71 | ALOX5 (0.46) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29229529 | 0.71 | CA12 (0.39) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL6450101 | 0.69 | ERN1 (0.59) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL6450098 | 0.69 | ERN1 (0.59) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL25432180 | 0.68 | CA12 (0.43) | CA12CA1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493587-B2 | Metal complexes of salan-type ligands and uses thereof as catalysts for polymerization of alpha-olefins | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-11-15 | — | — | US | disclosed |
| EP-2665755-A1 | METAL COMPLEXES OF SALAN-TYPE LIGANDS AND USES THEREOF AS CATALYSTS FOR POLYMERIZATION OF ALPHA-OLEFINS | Ramot at Tel Aviv University, Ltd. (IL) | 2013-11-27 | — | — | EP | disclosed |
| US-20130310529-A1 | METAL COMPLEXES OF SALAN-TYPE LIGANDS AND USES THEREOF AS CATALYSTS FOR POLYMERIZATION OF ALPHA-OLEFINS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2013-11-21 | — | — | US | disclosed |
| WO-2012098521-A1 | METAL COMPLEXES OF SALAN-TYPE LIGANDS AND USES THEREOF AS CATALYSTS FOR POLYMERIZATION OF ALPHA-OLEFINS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-07-26 | — | — | WO | disclosed |