Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11298525 | 1.00 | ALOX5 (0.46) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13321375 | 0.89 | ALOX5 (0.49) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL2221201 | 0.89 | ALOX5 (0.49) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29370004 | 0.89 | ALOX5 (0.49) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL2221207 | 0.89 | ALOX5 (0.49) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29535850 | 0.86 | ALOX5 (0.51) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3998711 | 0.86 | ALOX5 (0.51) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29785796 | 0.86 | ALOX5 (0.51) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3998710 | 0.86 | ALOX5 (0.51) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL23644507 | 0.85 | ALOX5 (0.46) | ALOX5PTGS2SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665755-A1 | METAL COMPLEXES OF SALAN-TYPE LIGANDS AND USES THEREOF AS CATALYSTS FOR POLYMERIZATION OF ALPHA-OLEFINS | Ramot at Tel Aviv University, Ltd. (IL) | 2013-11-27 | — | — | EP | disclosed |
| US-20130310529-A1 | METAL COMPLEXES OF SALAN-TYPE LIGANDS AND USES THEREOF AS CATALYSTS FOR POLYMERIZATION OF ALPHA-OLEFINS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2013-11-21 | — | — | US | disclosed |
| WO-2012098521-A1 | METAL COMPLEXES OF SALAN-TYPE LIGANDS AND USES THEREOF AS CATALYSTS FOR POLYMERIZATION OF ALPHA-OLEFINS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-07-26 | — | — | WO | disclosed |