Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30515123 | 0.93 | FFAR1 (0.41) | FFAR1GLAMRGPRX4SCN8ACNR1 | |
| SCHEMBL11304595 | 0.93 | PLA2G2A (0.46) | FFAR1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL25336781 | 0.89 | LPAR3 (0.56) | FFAR1GLALPAR1LPAR3LPAR2 | |
| SCHEMBL25336782 | 0.89 | LPAR3 (0.56) | FFAR1GLALPAR1LPAR3LPAR2 | |
| SCHEMBL30515139 | 0.89 | PLA2G2A (0.43) | FFAR1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL31069864 | 0.88 | FFAR1 (0.38) | FFAR1PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL11299159 | 0.81 | HTT (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL24304385 | 0.80 | USP2 (0.42) | CNR1CNR2LPAR1LPAR3LPAR2 | |
| SCHEMBL25337956 | 0.80 | FFAR1 (0.41) | FFAR1GLAMRGPRX4SCN8ACNR1 | |
| SCHEMBL10604578 | 0.80 | PLA2G10 (0.47) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262021-A | INDUCERS OF PRODUCTION OF INTERFERON | PFIZER INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4215146-A | Antiviral amine derivatives of glycerol and propanediols | PFIZER INC. (US) | 1980-07-29 | — | — | US | disclosed |
| US-4193999-A | Antiviral amine derivatives of propanediols | PFIZER INC. (US) | 1980-03-18 | — | — | US | disclosed |