Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.41 |
| ▸ | TLR2 | O60603 | 8/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304533 | 0.92 | PLA2G2A (0.48) | PLA2G2ATLR2LPAR1LPAR3PLA2G10 | |
| SCHEMBL11302035 | 0.92 | PLA2G2A (0.48) | PLA2G2ATLR2LPAR1LPAR3PLA2G10 | |
| Hydrochloric Acid SCHEMBL11308092 | 0.91 | PLA2G2A (0.47) | PLA2G2ATLR2LPAR1LPAR3PLA2G10 | |
| SCHEMBL10604671 | 0.83 | PLA2G10 (0.47) | PLA2G2ATLR2LPAR1LPAR3PLA2G10 | |
| SCHEMBL18641859 | 0.83 | PLA2G10 (0.47) | PLA2G2ATLR2LPAR1LPAR3PLA2G10 | |
| SCHEMBL10605748 | 0.83 | PLA2G10 (0.47) | PLA2G2ATLR2LPAR1LPAR3PLA2G10 | |
| SCHEMBL10604578 | 0.83 | PLA2G10 (0.47) | PLA2G2ATLR2LPAR1LPAR3PLA2G10 | |
| SCHEMBL11301693 | 0.81 | TSHR (0.44) | PLA2G2ATSHR | |
| SCHEMBL11298010 | 0.81 | FFAR1 (0.41) | PLA2G2ALPAR1LPAR3PLA2G10PLA2G1B | |
| SCHEMBL11300306 | 0.80 | TLR2 (0.49) | TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262021-A | INDUCERS OF PRODUCTION OF INTERFERON | PFIZER INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4215146-A | Antiviral amine derivatives of glycerol and propanediols | PFIZER INC. (US) | 1980-07-29 | — | — | US | disclosed |
| US-4193999-A | Antiviral amine derivatives of propanediols | PFIZER INC. (US) | 1980-03-18 | — | — | US | disclosed |