Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA9 | Q16790 | 6/20 | 0.39 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP8 | P22894 | 4/20 | 0.37 |
| ▸ | MMP3 | P08254 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | ENO1 | P06733 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299936 | 0.93 | MMP2 (0.39) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL2701491 | 0.81 | MMP2 (0.32) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL28379154 | 0.81 | CA1 (0.40) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL14328077 | 0.77 | ACE (0.41) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL14746631 | 0.75 | MMP2 (0.33) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL11300576 | 0.75 | DGAT1 (0.31) | — | |
| SCHEMBL10396838 | 0.74 | — | — | |
| SCHEMBL3481359 | 0.73 | — | — | |
| SCHEMBL18261819 | 0.71 | MMP2 (0.41) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL28446283 | 0.71 | MMP2 (0.41) | MMP2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254073-A | FROM DIPHOSPHONATES | SCM CORPORATION (US) | 1981-03-03 | — | — | US | claimed |
| US-4254073-A | FROM DIPHOSPHONATES | SCM CORPORATION (US) | 1981-03-03 | — | — | US | disclosed |