SCHEMBL11298249

SCHEMBL11298249

CC(=O)CC(O)C(O)C(=O)CO

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.43
TSHR P16473 1/20 0.43
ALDH1A1 P00352 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4360901 0.78 TSHR (0.50) CYP2C9TSHRTDP1
SCHEMBL27216228 0.78 TSHR (0.50) CYP2C9TSHRTDP1
SCHEMBL5542149 0.75 ALDH1A1 (0.43) CYP2C9TSHRALDH1A1TDP1
SCHEMBL7706176 0.75 TSHR (0.46) CYP2C9TSHR
Fructose SCHEMBL8025670 0.74 TDP1 (0.50) CYP2C9TSHRALDH1A1TDP1
SCHEMBL23723109 0.74 CYP2C9 (0.50) CYP2C9TSHRALDH1A1TDP1
SCHEMBL299290 0.74 CYP2C9 (0.50) CYP2C9TSHRALDH1A1TDP1
SCHEMBL37388 0.74 CYP2C9 (0.50) CYP2C9TSHRALDH1A1TDP1
SCHEMBL37387 0.74 CYP2C9 (0.50) CYP2C9TSHRALDH1A1TDP1
SCHEMBL3649734 0.74 CYP2C9 (0.50) CYP2C9TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0019843-B1 SISOMICIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES BAYER AG (DE) 1982-09-29 EP disclosed