Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP9 | P14780 | 5/20 | 0.44 |
| ▸ | MMP8 | P22894 | 5/20 | 0.44 |
| ▸ | MMP12 | P39900 | 5/20 | 0.44 |
| ▸ | MMP13 | P45452 | 5/20 | 0.44 |
| ▸ | MMP14 | P50281 | 4/20 | 0.44 |
| ▸ | MMP16 | P51512 | 4/20 | 0.44 |
| ▸ | MMP3 | P08254 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294969 | 0.88 | MMP2 (0.46) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11292388 | 0.86 | MMP2 (0.45) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11298903 | 0.86 | MMP2 (0.45) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11300247 | 0.85 | HTT (0.45) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11301335 | 0.85 | HTT (0.56) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11292405 | 0.85 | HTT (0.56) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL9817864 | 0.85 | HTT (0.56) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11301453 | 0.85 | MMP2 (0.44) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11295107 | 0.85 | HTT (0.46) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11295387 | 0.84 | HTT (0.50) | MMP2MMP9MMP8MMP14MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356325-A | Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-10-26 | — | — | US | disclosed |