Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | XBP1 | P17861 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 2/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300082 | 0.93 | MAP2 (0.62) | MAP2ALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL11557335 | 0.91 | MAP2 (0.54) | MAP2ALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL11305292 | 0.88 | MAP2 (0.54) | MAP2ALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL11307889 | 0.87 | MAP2 (0.52) | MAP2ALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL11555777 | 0.86 | MAP2 (0.48) | MAP2ALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL11343474 | 0.85 | ALDH1A1 (0.61) | MAP2ALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL11255054 | 0.84 | MAP2 (0.47) | MAP2ALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL11298462 | 0.84 | MAP2 (0.52) | MAP2ALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL11305349 | 0.84 | MAP2 (0.46) | MAP2ALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL11297232 | 0.83 | MAP2 (0.47) | MAP2ALDH1A1KDM4EHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255442-A | 2-[(Methylsulfinyl)]-3-phenylindoles | SCHERING CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| EP-0000972-A2 | 2-Substituted-3-phenylindoles, their preparation, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-03-07 | — | — | EP | disclosed |