Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 11/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555777 | 0.86 | MAP2 (0.48) | MAP2PTGS2ALDH1A1CYP1A2HPGD | |
| SCHEMBL11300082 | 0.85 | MAP2 (0.62) | MAP2PTGS2ALDH1A1CYP1A2HPGD | |
| SCHEMBL11298462 | 0.84 | MAP2 (0.52) | MAP2PTGS2ALDH1A1CYP1A2HPGD | |
| SCHEMBL11298671 | 0.83 | MAP2 (0.67) | MAP2PTGS2ALDH1A1CYP1A2HPGD | |
| SCHEMBL11305292 | 0.81 | MAP2 (0.54) | MAP2PTGS2ALDH1A1CYP1A2HPGD | |
| SCHEMBL11305349 | 0.81 | MAP2 (0.46) | MAP2PTGS2ALDH1A1CYP1A2HPGD | |
| SCHEMBL11301573 | 0.80 | MAP2 (0.46) | MAP2PTGS2ALDH1A1CYP1A2HPGD | |
| SCHEMBL11255054 | 0.80 | MAP2 (0.47) | MAP2PTGS2ALDH1A1CYP1A2HPGD | |
| SCHEMBL11303798 | 0.77 | ALDH1A1 (0.71) | MAP2ALDH1A1CYP1A2HPGDXBP1 | |
| SCHEMBL11306229 | 0.76 | PTGS2 (0.44) | MAP2PTGS2ALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255442-A | 2-[(Methylsulfinyl)]-3-phenylindoles | SCHERING CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| EP-0000972-A2 | 2-Substituted-3-phenylindoles, their preparation, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-03-07 | — | — | EP | disclosed |