Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556875 | 0.96 | MAP2 (0.45) | MAP2ALDH1A1HPGDGPR35CYP1A2 | |
| SCHEMBL11302781 | 0.91 | MAP2 (0.51) | MAP2ALDH1A1HPGDGPR35CYP1A2 | |
| SCHEMBL11256808 | 0.89 | MAP2 (0.36) | MAP2ALDH1A1HPGDGPR35CYP1A2 | |
| SCHEMBL11301446 | 0.89 | MAP2 (0.41) | MAP2GPR35CA1CA2 | |
| SCHEMBL11252557 | 0.88 | GPR35 (0.47) | MAP2ALDH1A1HPGDGPR35CYP1A2 | |
| SCHEMBL11300076 | 0.86 | CA1 (0.39) | MAP2ALDH1A1HPGDGPR35CYP1A2 | |
| SCHEMBL11309419 | 0.85 | MAP2 (0.44) | MAP2CA1CA2LMNASMN1; SMN2 | |
| SCHEMBL11307538 | 0.85 | MAP2 (0.47) | MAP2ALDH1A1HPGDGPR35CYP1A2 | |
| SCHEMBL11256027 | 0.84 | CSF1R (0.33) | MAP2MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL11255903 | 0.84 | MAP2 (0.31) | MAP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255442-A | 2-[(Methylsulfinyl)]-3-phenylindoles | SCHERING CORPORATION (US) | 1981-03-10 | — | — | US | claimed |
| EP-0000972-A2 | 2-Substituted-3-phenylindoles, their preparation, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-03-07 | — | — | EP | claimed |
| US-4255442-A | 2-[(Methylsulfinyl)]-3-phenylindoles | SCHERING CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| EP-0000972-A2 | 2-Substituted-3-phenylindoles, their preparation, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-03-07 | — | — | EP | disclosed |