Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 8/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | GPR17 | Q13304 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11298778 | 0.89 | MAP2 (0.47) | MAP2GPR35CA1CA2 | |
| SCHEMBL11256808 | 0.88 | MAP2 (0.36) | MAP2GPR35 | |
| SCHEMBL11556875 | 0.85 | MAP2 (0.45) | MAP2GPR35CA1CA2 | |
| SCHEMBL11306091 | 0.85 | MAP2 (0.40) | MAP2GPR35GPR17CA1CA2 | |
| SCHEMBL11302659 | 0.84 | MAP2 (0.53) | MAP2 | |
| SCHEMBL11309419 | 0.84 | MAP2 (0.44) | MAP2CA1CA2 | |
| SCHEMBL11304764 | 0.82 | MAP2 (0.42) | MAP2GPR35GPR17CA1CA2 | |
| SCHEMBL11252557 | 0.82 | GPR35 (0.47) | MAP2GPR35 | |
| SCHEMBL11256027 | 0.80 | CSF1R (0.33) | MAP2 | |
| SCHEMBL11300076 | 0.80 | CA1 (0.39) | MAP2GPR35CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255442-A | 2-[(Methylsulfinyl)]-3-phenylindoles | SCHERING CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| EP-0000972-A2 | 2-Substituted-3-phenylindoles, their preparation, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-03-07 | — | — | EP | disclosed |