SCHEMBL11298968

SCHEMBL11298968

Cc1ccc(C(=O)c2ccc(C)cc2[N+](=O)[O-])cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.63
MAPT P10636 2/20 0.63
HTT P42858 2/20 0.63
ABCC3 O15438 1/20 0.57
ABCC4 O15439 1/20 0.57
NR1I2 O75469 1/20 0.57
ABCB11 O95342 1/20 0.57
TTR P02766 1/20 0.57
NR3C1 P04150 1/20 0.57
PGR P06401 1/20 0.57
HTR1A P08908 1/20 0.57
ADORA3 P0DMS8 1/20 0.57
RARB P10826 1/20 0.57
COMT P21964 1/20 0.57
SLC6A2 P23975 1/20 0.57
ADORA1 P30542 1/20 0.57
ADRA1A P35348 1/20 0.57
PTGS2 P35354 1/20 0.57
SLC6A3 Q01959 1/20 0.57
KCNH2 Q12809 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7263800 0.90 ALDH1A1 (0.56) ALDH1A1MAPTHTTABCC3ABCC4
Methyl Alcohol SCHEMBL28215594 0.89 ALDH1A1 (0.55) ALDH1A1MAPTHTTABCC3ABCC4
SCHEMBL18779446 0.89 TSHR (0.62) ALDH1A1MAPTHTTABCC3ABCC4
SCHEMBL7262531 0.83 GAA (0.60) ALDH1A1MAPTHTTABCC3ABCC4
SCHEMBL28746583 0.83 ALDH1A1 (0.49) ALDH1A1MAPTHTTABCC3ABCC4
SCHEMBL18779429 0.83 KMT2A (0.58) ALDH1A1MAPTHTTABCC3ABCC4
Monoethanolamine SCHEMBL27927512 0.82 ALDH1A1 (0.48) ALDH1A1MAPTHTTABCC3ABCC4
Propionaldehyde SCHEMBL28746585 0.82 ALDH1A1 (0.48) ALDH1A1MAPTHTTSLC6A2SLC6A3
SCHEMBL3112702 0.81 TSHR (0.60) ALDH1A1MAPTHTTSLC6A2SLC6A3
SCHEMBL406111 0.81 TSHR (0.60) ALDH1A1GPR35TSHRCYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4352942-A TREATMENT OF ISOMERIC MIXTURE OF NITRO AROMATIC KETO COMPOUNDS WITH OLEUM GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-10-05 US disclosed