Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351520 | 0.74 | CYP2D6 (0.36) | MEN1KMT2AADRB3ADRB2ADRB1 | |
| Ammonia Solution, Strong SCHEMBL11251682 | 0.72 | MEN1 (0.43) | PTGS1SLC6A2KDM4EMEN1KMT2A | |
| SCHEMBL11299249 | 0.68 | MTNR1A (0.44) | PTGS1SLC6A2KDM4EMEN1KMT2A | |
| SCHEMBL19940639 | 0.68 | ESR1 (0.50) | PTGS1SLC6A2KDM4EMEN1KMT2A | |
| SCHEMBL11376493 | 0.67 | MEN1 (0.57) | SLC6A2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL57369 | 0.67 | MEN1 (0.57) | SLC6A2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10790889 | 0.66 | CYP2D6 (0.74) | PTGS1SLC6A2MEN1KMT2AADRB3 | |
| SCHEMBL26910 | 0.65 | MEN1 (0.55) | SLC6A2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL13057582 | 0.65 | ALDH1A1 (0.46) | PTGS1SLC6A2KDM4EMEN1KMT2A | |
| SCHEMBL1888745 | 0.65 | MEN1 (0.50) | SLC6A2KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007605-B1 | A PROCESS FOR INVERTING THE CONFIGURATION IN OPTICALLY ACTIVE COMPOUNDS AND OPTICALLY ACTIVE INTERMEDIATE COMPOUNDS AND THEIR SALTS REQUIRED THEREFOR | CIBA-GEIGY AG (CH) | 1982-09-15 | — | — | EP | disclosed |