Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11293961 | 0.91 | HDAC4 (0.41) | HDAC4HDAC2HDAC8ALDH1A1POLB | |
| SCHEMBL11294254 | 0.77 | F2 (0.40) | HDAC4HDAC2HDAC8ALDH1A1POLB | |
| SCHEMBL12786072 | 0.75 | HDAC4 (0.55) | HDAC4HDAC2HDAC8ALDH1A1KDM4E | |
| SCHEMBL11297857 | 0.74 | REN (0.39) | ALDH1A1KDM4ERENPTGS1PTGS2 | |
| SCHEMBL11297907 | 0.74 | PHGDH (0.30) | — | |
| SCHEMBL11304110 | 0.73 | PSMB5 (0.31) | — | |
| SCHEMBL11303526 | 0.73 | TDP1 (0.44) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL13144238 | 0.72 | HDAC4 (0.51) | HDAC4HDAC2HDAC8ALDH1A1KDM4E | |
| SCHEMBL11302460 | 0.72 | MEN1 (0.31) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL11296224 | 0.72 | HDAC8 (0.33) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261732-A | Alkyl and alkoxyalkyl N-3-alkyl and N-3,5-dialkylbenzoyl-N-isopropylaminoacetate herbicides | PPG INDUSTRIES, INC. (US) | 1981-04-14 | — | — | US | disclosed |