Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.39 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11296776 | 0.82 | REN (0.33) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL11305331 | 0.81 | HDAC8 (0.35) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL11294254 | 0.81 | F2 (0.40) | TP53BP1KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11299184 | 0.77 | HDAC8 (0.42) | — | |
| SCHEMBL11296820 | 0.77 | PPARG (0.41) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL11294066 | 0.77 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2 | |
| SCHEMBL11302460 | 0.75 | MEN1 (0.31) | ALDH1A1LMNA | |
| SCHEMBL11294344 | 0.75 | CYP4F2 (0.43) | LMNASMN1; SMN2KCNH2 | |
| SCHEMBL11299275 | 0.74 | HDAC4 (0.38) | RENKDM4EALDH1A1LMNAPTGS1 | |
| SCHEMBL11303530 | 0.74 | F2 (0.38) | RENHTR1AADRA1DHTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261732-A | Alkyl and alkoxyalkyl N-3-alkyl and N-3,5-dialkylbenzoyl-N-isopropylaminoacetate herbicides | PPG INDUSTRIES, INC. (US) | 1981-04-14 | — | — | US | disclosed |