Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266685 | 0.90 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| SCHEMBL11306067 | 0.89 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| SCHEMBL38314 | 0.85 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1RAB9ANPC1RECQL | |
| SCHEMBL51274 | 0.84 | GAA (0.54) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| SCHEMBL15006838 | 0.82 | HDAC1 (0.62) | ALDH1A1SRD5A2RAB9ANPC1RECQL | |
| SCHEMBL7077503 | 0.82 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1SRD5A2RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL28033163 | 0.81 | TSHR (0.46) | ALDH1A1SRD5A2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7722382 | 0.81 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| SCHEMBL26085771 | 0.80 | HDAC1 (0.64) | ALDH1A1SRD5A2RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11349193 | 0.79 | PLK1 (0.53) | ALDH1A1SRD5A2RAB9ANPC1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005530-B1 | NEW MERCAPTOPHENYLKETONES AND THEIR USE AS INITIATORS FOR THE PHOTOPOLYMERISATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | CIBA-GEIGY AG (CH) | 1982-05-12 | — | — | EP | disclosed |
| US-4279721-A | Mercaptophenyl ketones as initiators for the photopolymerization of ethylenically unsaturated compounds | CIBA-GEIGY CORPORATION (US) | 1981-07-21 | — | — | US | disclosed |
| EP-0005530-A1 | New mercaptophenylketones and their use as initiators for the photopolymerisation of ethylenically unsaturated compounds | CIBA-GEIGY AG (CH) | 1979-11-28 | — | — | EP | disclosed |