Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 6/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299425 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL376816 | 0.81 | ALDH1A1 (0.70) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3671919 | 0.79 | ALDH1A1 (0.67) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| Bromide SCHEMBL11192119 | 0.79 | ALDH1A1 (0.67) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15053055 | 0.79 | MCL1 (0.38) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3667550 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPK1NPC1RAB9ACYP1A2 | |
| Hydrochloric Acid SCHEMBL28033163 | 0.77 | TSHR (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL11266685 | 0.75 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2RECQL | |
| Phosphoric Acid SCHEMBL11703957 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL38313 | 0.74 | RAB9A (0.44) | ALDH1A1NPC1RAB9ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023957-B2 | Compound for use in peptide synthesis | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-05-05 | — | — | US | disclosed |
| US-20130131286-A1 | COMPOUND FOR USE IN PEPTIDE SYNTHESIS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-05-23 | — | — | US | disclosed |
| EP-2590939-A1 | COMPOUND FOR USE IN PEPTIDE SYNTHESIS | Nanyang Technological University (SG) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012005691-A1 | COMPOUND FOR USE IN PEPTIDE SYNTHESIS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131286-A1 | COMPOUND FOR USE IN PEPTIDE SYNTHESIS | PTMS, ANPEP, BCAT2 | ALDH1A1 4346/4885MAPK1 3468/4885NPC1 1685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.