SCHEMBL11299640

SCHEMBL11299640

CC1(C)CC(NC(=O)C(=O)N(N)C2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RECQL P46063 2/20 0.42
POLB P06746 3/20 0.42
GAA P10253 2/20 0.42
ALDH1A1 P00352 1/20 0.40
EZH2 Q15910 1/20 0.40
KMT2A Q03164 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HTT P42858 1/20 0.39
GLA P06280 1/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9643894 0.84 RECQL (0.45) RECQLPOLBGAAALDH1A1EZH2
SCHEMBL3295977 0.79 RECQL (0.57) RECQLPOLBGAAALDH1A1EZH2
SCHEMBL817041 0.78 ALOX15 (0.36) RECQLPOLBGAAKMT2AMEN1
SCHEMBL9200819 0.78 GAA (0.37) POLBGAAKMT2AMEN1
SCHEMBL3422383 0.76 RECQL (0.50) RECQLPOLBGAAALDH1A1EZH2
SCHEMBL9580304 0.76 POLB (0.44) RECQLPOLBGAAALDH1A1EZH2
SCHEMBL9823242 0.76 GAA (0.41) RECQLPOLBGAAALDH1A1EZH2
SCHEMBL2956173 0.75 GAA (0.50) RECQLPOLBGAAALDH1A1EZH2
SCHEMBL9154782 0.74 GAA (0.52) RECQLPOLBGAAALDH1A1EZH2
SCHEMBL9154314 0.74 GAA (0.52) RECQLPOLBGAAALDH1A1EZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015171709-A1 AMORPHOUS POLYESTER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-12 WO disclosed
EP-2665775-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC Innovative Plastics IP B.V. (NL) 2013-11-27 EP disclosed
WO-2012098513-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-26 WO disclosed