Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208678 | 0.82 | EPHX2 (0.36) | GAAHPGDSMN1; SMN2NPSR1LMNA | |
| SCHEMBL9580423 | 0.82 | HPGD (0.36) | GAAHPGDSMN1; SMN2NPSR1LMNA | |
| SCHEMBL9198372 | 0.80 | KDM4A (0.40) | GAAHPGDSMN1; SMN2NPSR1LMNA | |
| SCHEMBL9681791 | 0.79 | EPHX2 (0.39) | GAAEPHX2 | |
| SCHEMBL9198135 | 0.79 | EPHX2 (0.39) | GAAEPHX2 | |
| SCHEMBL11299640 | 0.78 | RECQL (0.42) | GAAPOLBMEN1KMT2A | |
| SCHEMBL9580438 | 0.76 | HPGD (0.31) | HPGDSMN1; SMN2NPSR1 | |
| SCHEMBL817041 | 0.75 | ALOX15 (0.36) | GAAPOLBMEN1KMT2AALOX15 | |
| SCHEMBL9580344 | 0.74 | — | — | |
| SCHEMBL9580305 | 0.72 | GAA (0.37) | GAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4117360-A | — | — | None | — | — | JP | disclosed |
| EP-0434079-B1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ATOCHEM NORTH AMERICA (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5213897-A | Curable coating compositions containing an N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazide | ELF ATOCHEM NORTH AMERICA, INC. | 1993-05-25 | — | — | US | disclosed |
| US-5132387-A | Polyme bound | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-07-21 | — | — | US | disclosed |
| EP-0494639-A2 | Hindered amine light stabilizer hydrazides for stabilizing polyurethane, polyurea and polyurethane-polyurea polymers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-07-15 | — | — | EP | disclosed |
| JP-H04117360-A | N,N'-HYDROCARBYLENEBIS(N-HALS-SUBSTITUTED AMIC ACID HYDRAZIDE) AND ITS DERIVATIVE | ATOCHEM NORTH AMERICA INC | 1992-04-17 | — | — | JP | disclosed |
| US-5043372-A | Light stabilizers for polyolefins; reacting hydrazine with bis(half ester-half amide) | ATOCHEM NORTH AMERICA, INC. (US) | 1991-08-27 | — | — | US | disclosed |
| EP-0434079-A1 | N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-06-26 | — | — | EP | disclosed |