Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311661 | 0.81 | S100A4 (0.68) | S100A4MAPTMEN1KMT2APARP1 | |
| SCHEMBL9615819 | 0.78 | CYP19A1 (0.53) | MAPTLMNANFE2L2BCHE | |
| SCHEMBL9615820 | 0.78 | CYP19A1 (0.53) | MAPTLMNANFE2L2BCHE | |
| SCHEMBL28009963 | 0.75 | TSHR (0.45) | S100A4MAPTMEN1KMT2AERN1 | |
| SCHEMBL7915296 | 0.74 | TDP1 (0.52) | MAPTMEN1KMT2AERN1LMNA | |
| SCHEMBL8623371 | 0.73 | MEN1 (0.65) | S100A4MAPTMEN1KMT2APARP1 | |
| SCHEMBL29903883 | 0.73 | MEN1 (0.65) | S100A4MAPTMEN1KMT2APARP1 | |
| SCHEMBL29450699 | 0.73 | MEN1 (0.65) | S100A4MAPTMEN1KMT2APARP1 | |
| SCHEMBL986883 | 0.73 | PADI4 (0.64) | MAPTMEN1KMT2AERN1LMNA | |
| SCHEMBL29588097 | 0.73 | PADI4 (0.64) | MAPTMEN1KMT2AERN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258181-A | BACTERICIDES, AMTITUMOR AGENTS, ANTICARCINOGENIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-24 | — | — | US | disclosed |