SCHEMBL7915296

SCHEMBL7915296

O=Cc1c([N+](=O)[O-])cc([N+](=O)[O-])c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.52
HPRT1 P00492 1/20 0.51
CTSB P07858 3/20 0.50
SIRT2 Q8IXJ6 1/20 0.50
TSHR P16473 1/20 0.49
ALDH1A1 P00352 4/20 0.46
MAPT P10636 3/20 0.44
HPGD P15428 3/20 0.44
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
GAA P10253 1/20 0.44
IDO1 P14902 1/20 0.44
TDO2 P48775 1/20 0.44
NPC1 O15118 1/20 0.44
S1PR4 O95977 1/20 0.44
S1PR1 P21453 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10363315 0.87 HPRT1 (0.47) TDP1HPRT1CTSBSIRT2TSHR
SCHEMBL3191280 0.86 CTSB (0.53) TDP1HPRT1CTSBSIRT2TSHR
SCHEMBL6245129 0.77 HPRT1 (0.78) TDP1HPRT1CTSBSIRT2TSHR
SCHEMBL31338905 0.76 ALDH1A1 (0.58) TDP1HPRT1CTSBTSHRALDH1A1
SCHEMBL5175572 0.76 ALDH1A1 (0.58) TDP1HPRT1CTSBTSHRALDH1A1
SCHEMBL28001454 0.75 ERN1 (0.56) CTSBCASP6ERN1
SCHEMBL11335429 0.74 CTSB (0.61) TDP1HPRT1CTSBSIRT2TSHR
SCHEMBL414254 0.74 TDP1 (0.54) TDP1HPRT1CTSBSIRT2TSHR
SCHEMBL5624830 0.74 TDP1 (0.54) TDP1HPRT1CTSBSIRT2TSHR
SCHEMBL8687725 0.74 CTSB (0.77) TDP1HPRT1CTSBSIRT2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed