Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21316593 | 0.92 | CA1 (0.39) | CA1CA2ZDHHC7CHRNB2CHRNA4 | |
| SCHEMBL19592430 | 0.91 | CA1 (0.38) | CA1CA2ZDHHC7CHRNB2CHRNA4 | |
| SCHEMBL18638573 | 0.85 | ZDHHC7 (0.50) | CA1CA2ZDHHC7LMNAPLA2G2C | |
| SCHEMBL12251292 | 0.84 | CA1 (0.37) | CA1CA2ZDHHC7CHRNB2CHRNA4 | |
| SCHEMBL14525672 | 0.78 | ALOX15 (0.42) | CA1CA2ZDHHC7CHRNB2CHRNA4 | |
| SCHEMBL13418848 | 0.76 | LMNA (0.57) | LMNASLC6A3TDP1TSHRALDH1A1 | |
| SCHEMBL126591 | 0.75 | — | — | |
| SCHEMBL13540974 | 0.75 | CA1 (0.39) | CA1CA2ZDHHC7CHRNB2CHRNA4 | |
| SCHEMBL5537593 | 0.73 | CA1 (0.38) | CA1CA2ZDHHC7CHRNB2CHRNA4 | |
| SCHEMBL11862679 | 0.73 | CA1 (0.47) | CA1CA2ZDHHC7HDAC7HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633265-B2 | UV stabilization of isosorbide polycarbonates | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-01-21 | — | — | US | disclosed |
| US-20120184651-A1 | UV Stabilization of Isosorbide Polycarbonates | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2012-07-19 | — | — | US | disclosed |
| US-7786246-B2 | Isosorbide-based polycarbonates, method of making, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-08-31 | — | — | US | disclosed |
| US-20100099832-A1 | ISOSORBIDE-BASED POLYCARBONATES, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-04-22 | — | — | US | disclosed |
| US-7671164-B2 | Aliphatic polycarbonates, methods of making, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-03-02 | — | — | US | disclosed |
| US-7666972-B2 | Isosorbide-based polycarbonates, method of making, and articles formed therefrom | SABIC Innovative Plastics IP B., V. (NL) | 2010-02-23 | — | — | US | disclosed |
| US-20090105393-A1 | ISOSORBIDE-BASED POLYCARBONATES, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2009-04-23 | — | — | US | disclosed |
| US-20090105443-A1 | ALIPHATIC POLYCARBONATES, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2009-04-23 | — | — | US | disclosed |