Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | CCNC | P24863 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294252 | 0.90 | MAPT (0.53) | MAPTALDH1A1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL11297538 | 0.90 | LMNA (0.55) | MAPTALDH1A1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL11412571 | 0.88 | KMT2A (0.53) | MAPTALDH1A1SMN1; SMN2KMT2ACCNC | |
| SCHEMBL9291194 | 0.88 | KMT2A (0.53) | MAPTALDH1A1SMN1; SMN2KMT2ACCNC | |
| SCHEMBL5961785 | 0.88 | KMT2A (0.53) | MAPTALDH1A1SMN1; SMN2KMT2ACCNC | |
| SCHEMBL11293455 | 0.88 | ALDH1A1 (0.56) | MAPTALDH1A1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL11299348 | 0.87 | LMNA (0.60) | MAPTALDH1A1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL11411199 | 0.87 | KMT2A (0.52) | MAPTALDH1A1SMN1; SMN2KMT2ACCNC | |
| SCHEMBL9905995 | 0.86 | ALDH1A1 (0.55) | MAPTALDH1A1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL11296728 | 0.86 | NPC1 (0.60) | MAPTALDH1A1SMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022882-B1 | ANISOTROPIC CARBOXYLIC-ACID-4-CYCLOHEXYLPHENYL ESTERS AND MIXTURES OF LIQUID CRYSTALS CONTAINING THEM | MERCK PATENT GmbH (DE) | 1982-12-15 | — | — | EP | disclosed |
| EP-0022882-A1 | Anisotropic carboxylic-acid-4-cyclohexylphenyl esters and mixtures of liquid crystals containing them | MERCK PATENT GmbH (DE) | 1981-01-28 | — | — | EP | disclosed |