Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 5/20 | 0.68 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.68 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.68 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.68 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.68 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.68 |
| ▸ | GPR183 | P32249 | 1/20 | 0.68 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.68 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.60 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TACR2 | P21452 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15960546 | 1.00 | TNNC1 (0.68) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL18885273 | 1.00 | TNNC1 (0.68) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL13890905 | 0.88 | SPHK2 (0.68) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL7622550 | 0.83 | S1PR1 (0.73) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL5989142 | 0.83 | S1PR1 (0.73) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL12696488 | 0.83 | S1PR1 (0.73) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL7615757 | 0.83 | S1PR1 (0.73) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL177208 | 0.82 | TNNC1 (0.68) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL7615978 | 0.81 | S1PR1 (0.74) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL7619659 | 0.81 | S1PR1 (0.74) | TNNC1S1PR1S1PR4S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815772-B2 | Process for the preparation of 2-amino-1,3-propane diol compounds and salts thereof | BIOCON LIMITED (IN) | 2017-11-14 | — | — | US | disclosed |
| US-20170073305-A1 | FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE | CATABASIS PHARMACEUTICALS, INC. | 2017-03-16 | — | — | US | disclosed |
| US-20150344430-A1 | METHODS OF LOWERING PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) | CATABASIS PHARMACEUTICALS, INC. | 2015-12-03 | — | — | US | disclosed |
| US-8766005-B2 | Process for producing fingolimod salts | RATIOPHARM GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20130059801-A1 | FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE | CATABASIS PHARMACEUTICALS, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-20120184617-A1 | PROCESS FOR PRODUCING FINGOLIMOD SALTS | RATIOPHARM GMBH (DE) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184617-A1 | PROCESS FOR PRODUCING FINGOLIMOD SALTS | S1PR4, S1PR2, S1PR3 | TNNC1 4322/4885S1PR1 4/4885S1PR4 1/4885 |
| US-20130059801-A1 | FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE | FASN, FADS1, ELOVL5 | TNNC1 967/4885S1PR1 765/4885S1PR4 874/4885 |
| US-20150344430-A1 | METHODS OF LOWERING PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) | PCSK9, PCSK6, PCSK7 | TNNC1 2093/4885S1PR1 503/4885S1PR4 545/4885 |
| US-20170073305-A1 | FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE | FASN, FADS1, ELOVL5 | TNNC1 967/4885S1PR1 765/4885S1PR4 874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.