Sugi Predict

Sugi Predict / Compounds / SCHEMBL1130100

SCHEMBL1130100

SCHEMBL1130100

C[Si](C)(Cl)Oc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA4 P22748 1/20 0.43
▸ LTA4H P09960 4/20 0.41
▸ TSHR P16473 1/20 0.41
▸ KCNA3 P22001 1/20 0.35
▸ CA5A P35218 1/20 0.33
▸ CA5B Q9Y2D0 1/20 0.33
▸ NPC1 O15118 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ LMNA P02545 2/20 0.32
▸ KCNH2 Q12809 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ GLA P06280 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ HTR1D P28221 1/20 0.32
▸ HTR1B P28222 1/20 0.32
▸ NR1H2 P55055 1/20 0.32
▸ BAX Q07812 1/20 0.32
▸ MAOA P21397 1/20 0.32
▸ NR1H4 Q96RI1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1130703 0.84 CA4 (0.43) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL1130623 0.84 CA4 (0.43) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL18108474 0.80 CA4 (0.40) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL18108197 0.80 CA4 (0.40) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL1130763 0.78 CA4 (0.39) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL18108112 0.78 CA4 (0.44) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL1042227 0.78 LTA4H (0.45) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL308311 0.78 CA4 (0.48) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL976629 0.78 CA4 (0.48) CA4LTA4HTSHRKCNA3CA5A
SCHEMBL9678425 0.78 CA4 (0.48) CA4LTA4HTSHRKCNA3CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4207424-A ALUMINA PRETREATED WITH SILYLATING AGENT AT ELEVATED TEMPERAUTRE HALCON RESEARCH & DEVELOPMENT CORPORATION (US) 1980-06-10 — — US claimed
CN-113637101-B Catalyst for alpha-olefin polymerization, preparation method and application 北京化工大学 2023-06-27 — — CN disclosed
US-20190332010-A1 ENERGY-SENSITIVE COMPOSITION, CURED PRODUCT, AND PATTERN FORMING METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2019-10-31 — — US disclosed
US-9884928-B2 Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group BRIDGESTONE CORPORATION (JP) 2018-02-06 — — US disclosed
US-20160289354-A1 POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP BRIDGESTONE CORPORATION (JP) 2016-10-06 — — US disclosed
EP-1323742-B1 Radiation sensitive refractive index changing composition and refractive index changing method JSR CORP (JP) 2011-02-16 — — EP disclosed
US-7525721-B2 Charged particle, microcapsule, electrophoretic device, electro-optical device, and method of forming a microcapsule SEIKO EPSON CORPORATION (JP) 2009-04-28 — — US disclosed
US-7205085-B2 Composition having permitivity being radiation-sensitively changeable and method for forming permitivity pattern JSR CORPORATION (JP) 2007-04-17 — — US disclosed
US-7125647-B2 Radiation-sensitive composition changing in refractive index and utilization thereof JSR CORPORATION (JP) 2006-10-24 — — US disclosed
US-7108954-B2 Radiation-sensitive composition changing in refractive index and method of changing refractive index JSR CORPORATION (JP) 2006-09-19 — — US disclosed
EP-1350814-A1 RADIATION-SENSITIVE COMPOSITION CHANGING IN REFRACTIVE INDEX AND METHOD OF CHANGING REFRACTIVE INDEX JSR Corporation (JP) 2003-10-08 — — EP disclosed
US-20030187119-A1 Radiation-sensitive composition capable of having refractive index distribution JSR CORPORATION (JP) 2003-10-02 — — US disclosed
US-20030171468-A1 Radiation-sensitive composition changing in refractive index and utilization thereof JSR CORPORATION (JP) 2003-09-11 — — US disclosed
US-20030139486-A1 Radiation sensitive refractive index changing composition and refractive index changing method JSR CORPORATION (JP) 2003-07-24 — — US disclosed
EP-1323742-A2 Radiation sensitive refractive index changing composition and refractive index changing method JSR Corporation (JP) 2003-07-02 — — EP disclosed
US-20030064303-A1 Composition having refractive index sensitively changeable by radiation and method for forming refractive index pattern JSR CORPORATION (JP) 2003-04-03 — — US disclosed
EP-1235104-A1 COMPOSITION HAVING REFRACTIVE INDEX SENSITIVELY CHANGEABLE BY RADIATION AND METHOD FOR FORMING REFRACTIVE INDEX PATTERN JSR Corporation (JP) 2002-08-28 — — EP disclosed
US-4210578-A LIGHT-STABILIZERS FOR PLASTICS CIBA-GEIGY CORPORATION (US) 1980-07-01 — — US disclosed
US-4207424-A ALUMINA PRETREATED WITH SILYLATING AGENT AT ELEVATED TEMPERAUTRE HALCON RESEARCH & DEVELOPMENT CORPORATION (US) 1980-06-10 — — US disclosed
US-4177186-A 4-SILOXY-DERIVATIVES OF STERICALLY HINDERED PIPERIDINES CIBA-GEIGY CORPORATION (US) 1979-12-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190332010-A1 ENERGY-SENSITIVE COMPOSITION, CURED PRODUCT, AND PATTERN FORMING METHOD KCNQ5, CACNA1A, KCNQ1 CA4 1765/4885LTA4H 1507/4885TSHR 4415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.