Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | CPA2 | P48052 | 1/20 | 0.34 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.30 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299619 | 0.94 | CPA1 (0.34) | CPA1CPA2CPA4NMT2NMT1 | |
| SCHEMBL11307612 | 0.90 | ANPEP (0.32) | — | |
| SCHEMBL11296860 | 0.88 | ANPEP (0.32) | — | |
| SCHEMBL11302281 | 0.86 | REN (0.34) | — | |
| SCHEMBL11298154 | 0.84 | PSMB5 (0.31) | — | |
| SCHEMBL11298731 | 0.81 | S1PR2 (0.33) | — | |
| SCHEMBL11300971 | 0.79 | S1PR2 (0.36) | — | |
| SCHEMBL11304618 | 0.78 | CYP2C9 (0.33) | — | |
| SCHEMBL11297035 | 0.78 | NPY4R (0.43) | — | |
| SCHEMBL11306826 | 0.76 | GRPR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026409-A1 | Combinations of active ingredients, pharmaceutical preparations, as well as their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-04-08 | — | — | EP | disclosed |
| US-4250085-A | PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | disclosed |