SCHEMBL11298154

SCHEMBL11298154

CNCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)P(=O)(O)O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 3/20 0.31
GPR139 Q6DWJ6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11307612 0.94 ANPEP (0.32)
SCHEMBL11296860 0.92 ANPEP (0.32)
SCHEMBL1582304 0.85 CTSC (0.34) PSMB5GPR139
SCHEMBL11301007 0.84 CPA1 (0.34)
SCHEMBL11303147 0.82 S1PR2 (0.33) PSMB5
SCHEMBL11302281 0.82 REN (0.34)
SCHEMBL11299619 0.81 CPA1 (0.34) PSMB5
SCHEMBL11306079 0.81 MMP1 (0.34) PSMB5
SCHEMBL11297767 0.80 FPR2 (0.34)
SCHEMBL11298731 0.79 S1PR2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0026409-A1 Combinations of active ingredients, pharmaceutical preparations, as well as their preparation F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-04-08 EP disclosed
US-4250085-A PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES HOFFMANN-LA ROCHE INC. (US) 1981-02-10 US disclosed