Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21494517 | 0.83 | MEN1 (0.51) | NPC1RAB9APKMKMT2ASMN1; SMN2 | |
| SCHEMBL28922624 | 0.80 | NPC1 (0.61) | NPC1RAB9APKMKMT2AHTR1A | |
| SCHEMBL29628844 | 0.76 | NPC1 (0.54) | NPC1RAB9APKMKMT2AHTR1A | |
| SCHEMBL10114090 | 0.76 | NPC1 (0.69) | NPC1RAB9APKMKMT2AHTR1A | |
| SCHEMBL6919888 | 0.75 | GAA (0.58) | RAB9APKMKMT2AMEN1LMNA | |
| SCHEMBL31563816 | 0.73 | NPC1 (0.58) | NPC1RAB9APKMKMT2AHTR1A | |
| Propionic Acid SCHEMBL1764372 | 0.72 | NPC1 (0.76) | NPC1RAB9APKMKMT2AHTR1A | |
| SCHEMBL4188221 | 0.72 | NPC1 (1.00) | NPC1RAB9APKMKMT2AHTR1A | |
| SCHEMBL29382376 | 0.72 | DPP4 (0.68) | RAB9AKMT2AHTTMEN1LMNA | |
| SCHEMBL987346 | 0.72 | DPP4 (0.68) | RAB9AKMT2AHTTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56043264-A | — | — | None | — | — | JP | disclosed |
| JP-S5643264-A | 1-OXOISOINDOLINE DERIVATIVE AND PREVENTIVE FOR PLANT DISEASE CONTAINING THE SAME AS THE EFFECTIVE COMPONENT | MEIJI SEIKA KAISHA LTD | 1981-04-21 | — | — | JP | disclosed |